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ABSTRACTrowth performance, total fish yield and economical evaluation of the grey mullet Mugil cephalus (L.) at different stocking densities were compared in monoculture system without any supplementary feeding. Four stocking densities at rate of 1050, 1400, 2100 and 4200 fish/feddan (0.42 ha) for treatments, T 1 , T 2 , T 3 and T 4 respectively, were carried out in eight freshwater earthen ponds. Ponds were fertilized with organic and inorganic fertilizers, (60 kg; chicken manure, 30 kg. super phosphate and 10.0kg urea per feddan biweekly). Results indicated that the main individual growth rate was highest for lower density and lowest for the higher density. Final body weight was 231.86, 182.82, 151.19 and 91.65 g /fish for T 1 , T 2 , T 3 and T 4 respectively, with significant difference (p<0.05).Final body length, SGR (%), RGR (%), daily weight gain, survival rate, condition factor, economic evaluation and sensitivity analysis were discussed. Total fish production values at the end of experimental period (180 days) were 233.7, 236.8, 273.0 and 313.9 kg. / feddan (0.42 ha.) for T 1 , T 2 , T 3 and T 4 respectively.It could be concluded that treatment (T 1 ) that received the lowest stocking density at the rate of 1050 grey mullet Mugil cephalus fingerlings per feddan (0.42 ha.), without any supplementary food, and cultured for 180 days in monoculture system, had the highest net return and rate of return, followed by T 2 and T 3 , which can reduce the risk for the farmer in the event of unexpected fall in market price or production or increasing of costs.

MATERIALS AND METHODS Collection of plant materials and preparation Plants have been the source for medicinal treatments for thousands of years. Whole plant samples of Lamiaceae species; Lavandula coronopifola, Ocimum basilicum, Ocimum filamentosum, Orthosiphon thymiflorus, Otostegia fruticosa, and Plectranthus asirensis (Figures 1-6 respectively) were collected from Jazan region, Kingdom of Saudi Arabia during April 2018. They were identified by the herbarium of the Biology Department, Faculty of Science, Jazan University. They were washed thoroughly 2-3 times with running tap water and then once with sterile water, ABSTRACT Deltamethrin is the most famous neurotoxic synthetic pyrethroid. The present work was mainly designed to evaluate the possible ameliorative role of melatonin against deltamethrin induced cerebellar neurotoxicity in pregnant rats and their offspring. In the present work, 24 pregnant Albino rats were divided into four groups (n=6). The control group received 1 ml/kg bw of ethanol (99%), the melatonin group received a daily oral dose of melatonin (10 mg/kg bw), deltamethrin treated group was received 12.5 mg/kg bw daily of deltamethrin and ameliorative group received deltamethrin simultaneously with melatonin. All groups were received their applicable dose from the 4th day of gestation till the end of weaning period (21 st day). The result of the present work revealed that deltamethrin can induce severe histopathological changes in the cerebellar cortex of pregnant rats and their offspring. The immunohistochemical results elucidated strong positive expression for GFAP and weak to moderate immune reaction for synaptophysin in the cerebellar cortex of deltamethrin treated mother's rats and their offspring. Moreover, in deltamethrin treated rats, the serum levels of antioxidants enzymes (SOD, CAT and GSH) as well as serotonin and glutamate showed highly significant decrease if compared with control. Cerebellar tissue analysis revealed that deltamethrin is implicated in induction of apoptosis that confirmed by increased activity of Caspse-3 and decreased activity of bcl 2. Post supplementation of melatonin to deltamethrin, successfully ameliorated the adverse histopathological, immmunohistochemical and biochemical changes in cerebellum of mother's rats and their offspring.