Purpose: This study was conducted to estimate the influence of knowledge of coronary artery disease (CAD) and self-efficacy on health behavior Compliance among patients with CAD.Methods: Data were collected from August 11, 2020 to April 28, 2021. In total, 159 patients with CAD participated in this study. Data were analyzed using the independent t-test, analysis of variance, Pearson correlation analysis, and multiple regression analysis.Results: Health behavior compliance was correlated with knowledge of CAD (r=.33, p<.001) and self-efficacy (r=.71, p<.001), Multiple regression analysis found self-efficacy (β=.67, p<.001) and knowledge of coronary artery disease (β=.16, p=.004), to be statistically significant influ encing factors, and the explanatory power of the model was approximately 52% (F=30.39, p<.001).Conclusion: Interventions to enhance self-efficacy and education programs to improve disease-related knowledge are essential for patients with CAD to improve their self-care health behaviors compliance.
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