The challenges posed by microbes in poultry industries and the continued search for natural means of combating them inspired this study. The effect of the stem bark extracts of Anacardium occidentale on avian colibacillosis was investigated. Ethanol and aqueous extracts of the stem bark of A. occidentale were prepared using standard methods. In vitro antimicrobial activities of the extracts were evaluated against E. coli. Nine groups of 10 broilers (day old chicks; 48 g – 50 g) each were created and bred for a period of eight weeks. Groups 1 to 3 served as the control, while group 4 to 9 served as the test groups. Meat quality, biochemical and haematological assessments were done using standard methods. The maximum zone of inhibition observed was 13.0±0.4 mm at 100 % concentration of the ethanol extract. Both extracts were observed to have a bactericidal / bacteriostatic ratio of 2. The extracts improved the meat quality, blood protein, liver enzymes and renal functions of the broilers compared to the negative control. Again, packed cell volume, haemoglobin and red blood cell counts were increased by the extracts compared to the negative control. On the whole, the results obtained for the extracts were not significantly different (p > 0.05) from that of the commercial antibiotics (positive control) results. Therefore, we can infer that crude extracts of A. occidentale could be used against Colibacillosis disease in place of the conventional commercial antibiotics.
Ethanol extract of pawpaw seed was evaluated for a possible application in the management of diabetes. Alloxan was used to induce diabetes in rats, which were subsequently used to study the antihyperglycaemic effect of the extract. Four (4) treatment groups and two (2) control groups of 8 rats each were created using complete randomized design. Triglyceride (TG), total cholesterol (TC), high density lipoprotein (HDL), low-density lipoprotein (LDL), total protein (TP), glutamic oxaloacetic transaminase (SGOT/AST), glutamic pyruvic transaminase (SGPT/ALT), alkaline phosphatase (ALP), urea and creatinine were studied using standard methods. A single dose of alloxan resulted in a significant increase (p < 0.05) in the serum TG, TC, LDL, AST, ALT, ALP, with a corresponding decrease in serum HDL, urea and creatinine. Following treatment with varying doses of the extract, there was a decrease in serum TG, TC, LDL, AST, ALT, ALP, and an increase in serum HDL, urea and creatinine. It could be inferred from the research outcome that crude extract of pawpaw seed (200 mg/kg extract) could be effective in the management of diabetes.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.