Dyschromatosis universalis hereditaria (DUH)is a rare genodermatosis. Generalized hyperpigmented and hypopigmented macules characterize its clinical appearence. It belongs to the group of dyschromatosis. Dyschromatosis symmetrica hereditaria (DHS) presents an acral distribution and unilateral dermatomal pigmentary disorder (UDPD) segmental lesions.
PHOTOLETTER TO THE EDITOR AbstractDyschromatosis universalis hereditaria (DUH) is a rare genodermatosis mainly described in asian subjects. Here, we report a case of a caucasian 11-year-old boy with DUH and an unaffected twin brother. Parents were not consanguineous. A review of the main phenotical, clinical and hystological aspects of this rare entity is exhibited. Differential diagnose might be stablished with several pigmentary disorders, so Dermatologist might have this entity in mind to make a correct diagnose, specially in cases with no response to typical treatments. (J Dermatol Case Rep. 2012; 6(3): 96-97) Key words: dyschromatosis, dyschromatosis universalis hereditaria, pigmentary disorder
Long-term CyA treatment might be necessary in some patients and this study shows that it could be sustained with a close follow-up. This involves regular visits depending on each patient, as well as common test protocol and clinical evaluation. In conclusion, this retrospective study seems to confirm the relative safety of long-term CyA treatment when patients are adequately monitored.
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