Efficient and cost-effective multiplexed detection schemes for proteins in small liquid samples would bring drastic advances to fields like disease detection or water quality monitoring. We present a novel multiplexed sensor with randomly deposited aptamer functionalized gold nanorods. The spectral position of plasmon resonances of individual nanorods, monitored by dark-field spectroscopy, respond specifically to different proteins. We demonstrate nanomolar sensitivity, sensor recycling, and the potential to upscale to hundreds or thousands of targets.

The reactions γp → ηp and γp → η 0 p are measured from their thresholds up to the center-of-mass energy W ¼ 1.96 GeV with the tagged-photon facilities at the Mainz Microtron, MAMI. Differential cross sections are obtained with unprecedented statistical accuracy, providing fine energy binning and full production-angle coverage. A strong cusp is observed in the total cross section for η photoproduction at the energies in the vicinity of the η 0 threshold, W ¼ 1896 MeV (E γ ¼ 1447 MeV). Within the framework of a revised ηMAID isobar model, the cusp, in connection with a steep rise of the η 0 total cross section from its threshold, can only be explained by a strong coupling of the poorly known Nð1895Þ1=2 − state to both ηp and η 0 p. Including the new high-accuracy results in the ηMAID fit to available η and η 0 photoproduction data allows the determination of the Nð1895Þ1=2 − properties.

The TRB3 features four FPGA-based TDCs with < 20 ps RMS time precision between two channels and 256+4+4 channels in total. One central FPGA provides flexible trigger functionality and GbE connectivity including powerful slow control. We present recent users' applications of this platform following the COME&KISS principle: successful test beamtimes at CERN (CBM), in Jülich and Mainz with an FPGA-based discriminator board (PaDiWa), a charge-to-width FEE board with high dynamic range, read-out of the n-XYTER ASIC and software for data unpacking and TDC calibration in ROOT. We conclude with an outlook on future developments.

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Measurement of the ω → π 0 e + e − and η → e + e − γ Dalitz decays with the A2 setup at MAMI The Dalitz decays η → e + e − γ and ω → π 0 e + e − have been measured in the γp → ηp and γp → ωp reactions, respectively, with the A2 tagged-photon facility at the Mainz Microtron, MAMI. The value obtained for the slope parameter of the electromagnetic transition form factor of η, Λ −2 η = (1.97 ± 0.11tot ) GeV −2 , is in good agreement with previous measurements of the η → e + e − γ and η → µ + µ − γ decays. The uncertainty obtained in the value of Λ −2 η is lower than in previous results based on the η → e + e − γ decay. The value obtained for the ω slope parameter, Λ −2 ωπ 0 = (1.99 ± 0.21tot) GeV −2 , is somewhat lower than previous measurements based on ω → π 0 µ + µ − , but the results for the ω transition form factor are in better agreement with theoretical calculations, compared to earlier experiments.