The obtained results demonstrate that our compound can serve as a base for further structure optimization in order to design new high-effective antimetastatic and antitumor agents.
It was established that cytochromeoxidase activity of Lewis carcinomaprimary culture at 14thday was 2,4 ± 0,15 mmolcyt.c/mg*min, and it was decrease dalmostat 7-fold (p <0.01) at 25thday, where as succinate dehydrogenase activity at 25thday was decreased to 21.7 ± 2.3mmolK3 [Fe (CN)6]/mg*min, which was at 1.6 fold less than at 14th day.
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