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Centralization of production facilities to increase productivity has led to plants with astronomical capacities. This development poses difficult tasks of respecting sanitary production and cleaning procedures. Cleaning Systems form an integrated part of modern production plants and are key elements to increase productivity. Automated CIP Systems deliver solutions at consistent flow rates, temperatures and at the appropriate concentration to a specific part of the plant. Total CIP effectiveness cannot be attributed solely to these parameters, as the plant design characteristics plays a vital role. Choice of components used, piping design and cleaning procedures implemented contribute to the overall performance of a cleaning process and are instrumental in reducing the quantity, COD and BOD values of waste-water generated. The following presentation outlines modern principles of CIP systems and the influence of plant design characteristics to improve the overall cleaning efficiency and increase productivity. Paper published with permission.