1585seen from Table VI, the values for the digested sera obtained by A1F MAS and the ISE show fairly good agreement, while the values for the digested sera are slightly larger than those for the nondigested sera obtained by AlF MAS. There may be a possibility that the differences of analytical results for nondigested and digested sera originate from contamination during the complicated procedures of dry ashing or from the existence of another form of fluorine; e.g., volatile organic fluorine compounds which may not be detected by AlF MAS.However, since A1F MAS has less chance of contamination because of its simplicity and rapidity, the present results may strongly support the existence of fluorine bound to protein, which was suggested by Taves (2, 3 ) .ACKNOWLEDGMENT T h e authors thank to S. Kamei for providing the blood serum samdes. We also exmess our thanks to S. Fuiiwara Taves, D. R. Nature (London) 1968, 220, 582-583. Taves, D. R. Talanta 1966, 75, 969-974.
The remarkable detection power of inductively coupled plasma mass spectrometry (ICP-MS) was demonstrated b y the analysis of an open ocean sea water reference material (with the acronym NASS-2). A 50-fold pre-concentration of several trace metals in the sea water was realised b y their adsorption o n t o silica-immobilised 8-hydroxyquinoline, which separates the elements of interest f r o m the bulk of the alkali and alkaline earth elements. The isotope dilution technique was used for the determination of seven elements (Ni, Cu, Zn, Mo, Cd, Pb and U). Accurate results were obtained for all of these elements except for Mo, with concentrations ranging between 0.027 and 11.5 pg 1-1.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.