Neurologic deterioration and DRESS occurred as severe adverse drug effects of daclizumab treatment. Early diagnosis and treatment of DRESS are essential because it is associated with complications such as new autoimmune diseases and liver failure, and may even be lethal. Because of its potential serious side effects, daclizumab was recently suspended for use in the European Union.
In the title compound, C25H17NO3S3, the mean planes of the thieno[2,3-b]carbazole and phenyl rings are inclined at an angle of 63.6 (1)°. The molecular structure features short intramolecular C—H⋯O contacts and the crystal packing exhibits weak intermolecular C—H⋯S and π–π interactions [centroid-to-centroid distances 3.734 (2)–3.888 (2) Å].
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