In a search for promising antifungal compounds, nine new 3,3'‐ethylenebis(5‐alkyl‐1,3,5‐thiadiazine‐2‐thiones) were synthesized by the reaction of ethylene diamine, carbon disulfide, formaldehyde, and the appropriate alkyl amine. The title compounds were tested for their antifungal activity in vitro against pathogenic (Trichophyton rubrum and Candida albicans), phytopathogenic (Penicillum expansum, Trichoderma hazianum, and Fasarium oxysporum), and aflatoxin producing (Aspergillus flavus) fungi. These compounds exhibited varied inhibitory effects on growth or sporulation of some tested fungal species.

No abstract

New 2H-Tetrahydro-1,3,5-thiadiazine-2-thiones Incorporating Glycine and Glycinamide as Potential Antifungal Agents. -The title compound (Vc) shows the highest activity against growth and sporulation of most of the tested species. -(ABOUL-FADL, T.; HUSSEIN, M. A.; EL-SHORBAGI*, A.-N.; KHALLIL, A.-R.; Arch. Pharm. (Weinheim, Ger.) 335 (2002) 9, 438-442; Fac. Pharm., Assiut Univ., Assiut 71526, Egypt; Eng.) -K. Schneider 13-159

No abstract

No abstract

One hundred and eleven identified and seven unidentified species in addition to 5 varieties belonging to forty-three aquatic fungal genera were recovered from 452 soil samples collected randomly from different localities in Nile Delta and Suez canal regions including eleven governorates. The investigated soil samples were collected seasonally during the period from autumn 1990 to summer 1991 (1 13 samples each season). The richest season (85 identified and 5 unidentified species in addition to 2 varieties) in aquatic fungi was the winter season (10.0-15.5 "C) whereas the poorest (32 identified and 5 unidentified species in addition to one variety) was summer (24.0-27.5 "C). The richest soil samples in aquatic fungi were those of low or moderate temperature seasons, high contents of organic matter and considerably poor in total soluble salts. The pH value did not show any regular seasonal variation and did not exhibit any considerable influence on fungal populations. Some aquatic fungal genera and species were disappeared completely in certain seasons and vice versa.The most dominant aquatic fungal genera were Pythium, Allomyces, Aqualinderella and Nowakowskiella. The commonest aquatic fungal species were Allomyces anomalus, Aqualinderella fermentans, Nowakowskiella elegans, Blastocladiopsis parva and Dictyuchus sterilis.The seasonal fluctuations of aquatic fungi were followed in various parts of the world (e.g.

No abstract

Thiadiazine derivativesThiadiazine derivatives R 0660Synthesis, Degradation Kinetics and in vitro Antimicrobial Activity of Tetrahydro-2H-1,3,5-thiadiazine-2-thione Derivatives of Some β-Amino Acids. -Title compounds (V) are obtained by incorporation of β-alanine (IVa) and β-phenylalanine (IVb), respectively, at the N-5 position of the heterocyclic moiety. -(ABOUL-FADL*, T.; KHALLIL, A.-R.; Arzneim.-Forsch. 53 (2003) 7, 526-531; Dep. Pharm. Med. Chem., Fac. Pharm., Assiut Univ., Assiut 71526, Egypt; Eng.) -H. Haber 42-166