(Anesth Analg. 2022;134:624–632)
Cervical cerclage, an operation designed to reduce preterm delivery and improve perinatal outcomes, often utilizes spinal anesthesia. While the benefits of spinal anesthesia are well documented, an intrathecal local anesthetic agent, such as 2-chloroprocaine (2-CP), could shorten postanesthesia care unit stay as it has a fast onset and short duration. Currently, bupivacaine is commonly used during spinal anesthesia because of historical concern regarding 2-CP’s safety. This study randomly compared the outcome of 2-CP 3% 50 mg and hyperbaric bupivacaine 0.75% 9 mg on dermatomal level, sensory block resolution, ability to ambulate and void, and motor blockade.
Programmed intermittent epidural bolus for labor analgesia during first stage of labor: a biased-coin up-and-down sequential allocation trial to determine the optimum interval time between boluses of a fixed volume of 10 mL of bupivacaine 0.0625% with fentanyl 2 μg/mL" a follow-up study was done with. Anesth Analg. 2017;124:537-541. 7. Zhou SQ, Wang J, Du WJ, et al. Optimum interval time of programmed intermittent epidural bolus of ropivacaine 0.08% with sufentanyl 0.3ug/mL for labor analgesia: a biased-coin up and down sequential allocation trial.
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