The COVID-19 pandemic has wreaked havoc on the whole world, taking over half a million lives and capsizing the world economy in unprecedented magnitudes. With the world scampering for a possible vaccine, early detection and containment are the only redress. Existing diagnostic technologies with high accuracy like RT-PCRs are expensive and sophisticated, requiring skilled individuals for specimen collection and screening, resulting in lower outreach. So, methods excluding direct human intervention are much sought after, and artificial intelligence-driven automated diagnosis, especially with radiography images, captured the researchers’ interest. This survey marks a detailed inspection of the deep learning–based automated detection of COVID-19 works done to date, a comparison of the available datasets, methodical challenges like imbalanced datasets and others, along with probable solutions with different preprocessing methods, and scopes of future exploration in this arena. We also benchmarked the performance of 315 deep models in diagnosing COVID-19, normal, and pneumonia from X-ray images of a custom dataset created from four others. The dataset is publicly available at https://github.com/rgbnihal2/COVID-19-X-ray-Dataset . Our results show that DenseNet201 model with Quadratic SVM classifier performs the best (accuracy: 98.16%, sensitivity: 98.93%, specificity: 98.77%) and maintains high accuracies in other similar architectures as well. This proves that even though radiography images might not be conclusive for radiologists, but it is so for deep learning algorithms for detecting COVID-19. We hope this extensive review will provide a comprehensive guideline for researchers in this field.

In the updated version of the paper, more experiments and result are illustrated. We also introduce a new chapter (Image Preprocessing) in Section 7. We also added two new tables (Table 4 and Table 6), one figure (Figure 4) and renewed Table 1, 2, and 7 and Figure 5. We also edited many things throughout the paper: rewriting Abstract, Data Description, and Conclusion; Adding more datasets description in Section 5; updating method and analysis of result. The COVID-19 pandemic has wreaked havoc on the whole world, taking over half a million lives and capsizing the world economy in unprecedented magnitudes. With the world scampering for a possible vaccine, early detection and containment is the only redress. Existing diagnostic technologies with high accuracy like RT-PCRs are expensive and sophisticated, requiring skilled individuals for specimen collection and screening, resulting in lower outreach. So, methods excluding direct human intervention are much sought after, and artificial intelligence-driven automated diagnosis, especially with radiography images, captured the researchers' interest. This survey marks a detailed inspection of the deep-learning-based automated detection of COVID-19 works done to date, a comparison of the available datasets, methodical challenges like imbalanced datasets and others, along with probable solutions with different preprocessing methods, and scopes of future exploration in this arena. We also benchmarked the performance of 315 deep models in diagnosing COVID-19, Normal, and Pneumonia from x-ray images of a custom dataset created from four others. The dataset is publicly available at https://github.com/rgbnihal2/COVID-19-X-ray-Dataset. Our results show that DenseNet201 model with Quadratic SVM classifier performs the best (accuracy: 98.16%, sensitivity: 98.93%, specificity: 98.77%) and maintains high accuracies in other similar architectures as well. This proves that even though radiography images might not be conclusive for radiologists, but it is so for deep learning algorithms for detecting COVID-19. We hope this extensive review will provide a comprehensive guideline for researchers in this field.

Post-stroke therapy restores lost skills. Traditionally, patients are supported by skilled therapists who monitor their progress and evaluate the program's effectiveness. Due to a shortage of qualified therapists, rehabilitation facilities are both expensive and inadequate. Furthermore, evaluations may be subjective and prone to errors. These limitations motivate the researchers to devise automated systems with minimal human intervention, therapistlike assessment, and broader outreach. This article reviews seminal works from 2013 onwards, qualitatively and quantitatively adapting the PRISMA approach to examine the potential of robot-assisted, virtual reality-based rehabilitation and automated assessments through data-driven learning. Extensive experimentation on KIMORE and UI-PRMD datasets reveal high agreement between automated methods and therapists. Our investigation shows that deep learning with spatio-temporal skeleton data and dynamic attention outperforms others, with an RMSE as low as 0.55. Fully automated rehabilitation is still in development, but, being an active research topic, it could hasten objective assessment and improve outreach.

The ravage of COVID-19 is not merely limited to taking its toll with half a million fatalities. It has halted the world economy, disrupting normalcy of lives with supervening severity than any other global catastrophe of the last few decades. The majority of the vaccine discovery attempts are still on trial, making early detection and containment the only feasible redress. The existing diagnostic technique with high accuracy has the setbacks of being expensive and sophisticated, requiring skilled individuals for specimen collection and screening resulting in lower outreach. So, methods excluding direct human intervention are much sought after, and artificial intelligence-driven automated diagnosis, especially with radiography images, captures the researchers' interest. This survey marks a detailed inspection of the deep-learning-based automated detection of COVID-19 works done to date, methodical challenges along with probable solutions, and scopes of future exploration in this arena. We also provided a comparative quantitative analysis of the performance of 315 deep models in diagnosing COVID-19, Normal, and Pneumonia from x-ray images. Our results show that Densenet201 model with Quadratic SVM classifier performs the best (accuracy: 98.16\%, sensitivity: 98.93\%, specificity: 98.77\%) and maintains high accuracies in other similar architectures as well. This proves that even though radiography images might not be conclusive for radiologists, but it is so for deep learning algorithms for detecting COVID-19. We hope this extensive review will provide a comprehensive guideline for researchers in this field.

Promoter region plays an important role in controlling gene expression of any living organism. It regulates gene transcription by providing space to the RNA polymerase and transcription factors to bind and interact with. Binding of appropriate transcription initiation complex is determined by the specific promoter sequence carrying gene specific motifs. The promoter recognition process is a part of the complex process where genes interact with each other over time and actually regulates the whole working process of a cell. Thus computational method for identifying promoter is a focal point for researchers. This paper presents an algorithm for identifying Drosophila melanogaster promoter using differential positional frequency matrix between promoter and non-promoter sequences which shows maximum 90.36% tenfold cross validation accuracy. The proposed method exhibits greater accuracy for detecting promoters. Also higher sensitivity and specificity results elucidate that the proposed method is less prone to false negatives and false positives compared to some other existing methods.