A case of papillary thyroid carcinoma arising in a thyroglossal duct cyst is presented. The tumour is rare and is generally not expected preoperatively. The clinical and pathological characteristics are emphasized, the treatment is discussed, and the importance of excision of thyroglossal duct cysts is stressed.
A prospective open and controlled study of perioperative antibiotics was conducted in patients with chronic otitis media (COM). Drug efficacy was found in a subgroup of 26 patients, who were characterized by preoperative aural drainage culturing Pseudomonas aeruginosa. Fourteen of these patients were randomized to receive ceftazidime (cephalosporin) for 5 days at the operation, while 12 had no antibiotic treatment. The occurrence of subsequent aural drainage was compared with the actual clinical and microbiological conditions of the ears 2 months after the operation; statistically significant differences were found in favor of the group treated with ceftazidime. Further studies must define the role of ceftazidime and other antibiotics in the management of patients with COM.
Nasal obstruction influences respiration during sleep and nasal packs may cause obstructive sleep apnoea. In order to investigate this, the perioperative oxygen saturation was monitored for 3 nights with continuous pulse oximetry in 12 patients, who had bilateral nasal packs after septoplasty. A significant increase in the number of nocturnal episodes of hypoxia and a significant prolongation of the mean duration of the individual hypoxic periods were demonstrated during the first and the second post-operative nights. The clinical significance of these results is as yet unknown, but the use of partial nasal packing in septoplasty is advocated. Further investigations of nocturnal oxygen desaturation and design of nasal packs, securing the post-operative nasal airway, are needed.
Nasal obstruction influences respiration during sleep and post-operative nasal packing may cause nocturnal oxygen desaturation and obstructive sleep apnoea. In order to investigate the influence of nasal packing with airway tubes on post-operative hypoxia during sleep, the oxygen saturation was monitored perioperatively in 18 patients, undergoing septoplasty followed by nasal packing using Merocel packs with airway tubes. For the group as a whole, no significant perioperative change of either median minimal or median mean oxygen desaturation could be demonstrated. A similar, non-significant perioperative prolongation of the relative time of nocturnal oxygen desaturation, expressed as per cent of the total nocturnal observation time, was seen. The results indicate that nasal packing with airway tubes may prevent post-operative hypoxia during sleep, but further investigation of post-operative nocturnal hypoxia and nasal packs, is needed.
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