Summary
It has been suggested that an important factor in the formation of renal calculi is a deficiency of citrate excretion by the kidney. This we have failed to confirm and consider rather that any gross diminution of urinary citrate is due simply to infection of the urinary tract. The proof of this is as follows:‐
1. In seven patients with calculi and a sterile tract the average citrate content of the urine was comparable with that found in controls.
2. Seven patients with calculi, associated with infection, were all found to have less citrate in their urine than normals.
3. Experiments in vitro confirmed that in this latter group citrate was destroyed particularly by E. colz, although with Kosers medium this splitting action was not detectable.
ye le pansay, Dieu le guarit ' -AMBRO' I' SE PAR6 (I 5 10-1 590) SUMMARY This paper relates the results of a clinical investigation into the value of suction drainage in general surgery which has covered 5 years and was conducted under some measure of control.The number of drained wounds observed is 1193; the results obtained show that the method produces great improvement in the healing of operations on the genito-urinary tract. In operations on the breast and thyroid, in herniotomies in which drainage has been indicated, and in a miscellaneous group, some improvement has been noted clinically. In the biliary tract fringe benefits have also occurred, but in these five groups statistical analysis of the figures obtained has not disclosed truly significant differences.It has not been found satisfactory in operations involving the lumen of the alimentary tract or in cases where frank infection with purulent exudate was present at operation.The results of two other investigations are also shown. One related to comparative studies of Lugol's solution, iodophor solution, and antibiotic sprays as methods of preoperative preparation, and the other to the time of the preliminary preoperative skin preparation and the effect this may have on wound healing.
Every surgical operation is an experiment in bacteriology. W e must realise that itis also an experiment in human biology.--F~NcIs D. MOORE and MARGARET R. BALL --BLOWERS, R., GARROD, L. P., and SHOOTER, R. A. (1960), Hospital Infection, Cause and Prevention. 2, 1039. Brit. med. J., 2, 798. med. Ass., 166, 1552. 3 . 3 2, 151. 1065. (1955)~ Lancet, 2, 786. Ancillary Room, ed.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.