Abstract:The study which employed both questionnaire and observational survey was conducted in urban and per urban area of Hossana with the objectives of determining the prevalence of major reproductive health problems of dairy cattle and the possible risk factors in the selected dairy farms from November 2013 to April 2014. A total of 390 dairy cattle (349 cross and 41 local breed) which were kept under different management system (256 intensively, 60 semi intensively and 74 were extensive) were included, out of which 43.07 % (n=168) were found to be affected either with one or more of reproductive problems. Repeat breeder, anoestrus, Retained Fetal membrane (RFM), and dystocia were found to be the major reproductive health problems containing 13.08%, 12.06%, 7.18% and 5.9% prevalence rate respectively and other reproductive health problems observed with lower prevalence include vaginal prolapsed, abortion, mixed and uterine prolapsed having 3.44%, 2.56%, 1.03%, and 0.76% respectively in the study farms of the area. The overall prevalence of reproductive problems showed significant difference (p<0.05) with respect to body condition and parity of dairy cattle where major reproductive health problems were observed more frequently in poor body conditioned and pluriparus cows. Whereas breed and management system were not found to have a significant influence (p>0.05) on the occurrence of reproductive problems in the area. Therefore, it is recommended that awareness creation to farm owners, attendants and improved management such as, proper feeding, accurate heat detection, considering the size of sire and dam while using AI, and health management should be improved to minimize the occurrence of these problems and associated economic losses in the dairy farms of the area.