It is estimated that about 10% of patients who have been infected with
SARS-CoV-2 worldwide suffer from Long-Covid, about 65 million people
[1]. Although we are beginning to know its pathophysiology, there is
still no evidence on its treatment. We present the case of a patient
with persistent prolonged symptoms who had an optimal response to
nirmatrelvir/ritonavir 2 years after acute infection.
Skin and soft tissue infections (SSTIs), and particularly diabetic-related foot infections (DFI), present diagnostic and therapeutic complexities, often leading to severe complications. This study aims to evaluate the in vitro efficacy of cefditoren and amoxicillin/clavulanic acid against typical DFI pathogens. Clinical samples from 40 patients with mild SSTIs were analyzed, revealing a predominance of Staphylococcus spp. and Streptococcus spp. species. Cefditoren exhibited activity against 90% of isolates, with superior potency over amoxicillin/clavulanic acid. These findings underscore the utility of cefditoren in empirical treatment of DFI, although a larger sample size would be desirable for further validation.
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