The biodistribution of radiomanganese (54Mn) was studied in mice, rats, and dogs. Disappearance of radioactivity from the blood was extremely rapid, with a half-time of approximately 0.8 minutes. This resulted in very favorable myocardium-to-blood ratios, even at early times after administration. The myocardial uptake in dogs was greater than 3% at three and 15 minutes, with myocardium-to-blood ratios of about 40:1 at 15 minutes. Positron tomograms obtained with 52mMn clearly demonstrated regional myocardial perfusion. There was good correlation (r = 0.89) of microsphere-to-radiomanganese distribution in the infarcted dog heart.

8. African Americans with translocation t(11;14) have superior survival after autologous hematopoietic cell transplantation for multiple myeloma in comparison with Whites in the United States -Badar --Cancer -Wiley Online Library [Internet]. [cited 2020 Nov 16].

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Is your abstract a video?: No Does this abstract contain original data?: Yes Please enter preferred presentation type: Poster Only Do you qualify and would you like to apply for the DDF travel bursary: No County of Residence: United Kingdom Introduction: Magnetic Resonance Cholangiopancreatography (MRCP) is increasingly used in the diagnosis of biliary abnormalities, particularly in stone disease 1 . However initial studies into its role in the absence of a dilated biliary system on initial imaging have demonstrated a low diagnostic yield 2 . The aim of this study was to further assess the role of MRCP when the biliary tree is non-dilated on index imaging. The factors associated with diagnostic yield in this setting are unclear. Method: We performed a retrospective observational study of consecutive MRCP studies (n=375) performed between October 2010 and June 2013 at West Middlesex University Hospital using electronic medical records. All MRCPs were reported by a consultant gastrointestinal radiologist. MRCP findings were correlated with the presence of dilated or nondilated biliary tree on initial imaging (USS/CT), jaundice (bilirubin > 21 μmol/L), transaminitis (alanine transaminase >45iu/L, aspartate transaminase >34iu/L), raised alkaline phosphatase (>120iu/L) and abdominal pain, and demographics including age and gender. Multivariate logistic regression analysis was performed using SPSS software. Results: The study included 243 female and 132 male patients with a mean age of 62 (range 20-101) years. There were 153 patients with biochemical jaundice, 246 with a dilated biliary system and 129 with a non-dilated system. The sensitivity of MRCP was 81%, with a specificity of 80%. Multivariate analysis identified that age (p=0.0253), the presence of jaundice (p=0.0247), and abnormal index imaging (p=0.0003), are statistically significant predictors of the finding of biliary tree abnormalities on subsequent MRCP (see attached table)