The
Raman spectra of polycrystalline samples of (RS)-2-(4-isobutylphenyl)-propionic
acid of the common name ibuprofen
have been measured in the temperature range 5–300 K. In the
low-frequency spectrum of the normal C12H17(COOH)
and deuterated C12H17(COOD) species, modes with
∼103 and ∼95 cm–1 wavenumbers were
detected, which corresponded to translational vibrations of O–H(D)···O
hydrogen bonds of two different tautomers: left L and right R, respectively. At temperatures below 150 K, only the L-tautomer
is found, and at T ≥ 150 K, both tautomers
are observed. The energy difference ΔE of the
ground vibrational state of potential minima for L- and R-tautomers
is ∼80 meV for COOH and ∼70 meV for COOD. At T ≥ 150 K, the vibrational frequency of the CO
bond in the COOH moiety exhibits an unusual temperature dependence.
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