BACKGROUND AND OBJECTIVES:Studies on exercise-induced bronchoconstriction (EIB) in team sports are lacking. The aim of this study was to screen for EIB among amateur teenage football players in Tunisia and to compare EIB prevalence between regions.METHODS:One hundred ninety-six male football players (mean age [SD], 13.5 [0.5] yrs), practicing in three different cities of Tunisia (Tunis, Sousse and Sfax), underwent an outdoor free run of 7 minutes. Forced expiratory volume in one second (FEV1) was recorded prior to and at 0, 3, 5, 10, 15, 20 and 30 minutes after the run. Players were screened for EIB positivity defined as a greater than 10% decline in FEV1 from the resting value at any timepoint.RESULTS:FEV1 decreased more than 10% in 30% of the players. EIB positivity was more common in Sfax (15.8%) than in Tunis (7.7%) (P =.03). Air humidity during the study was higher in Tunis.CONCLUSION:EIB is prevalent among amateur teenage football players in Tunisia. The prevalence differs between regions and seems to be dependent on air humidity levels.
cCRT. New treatment arms evaluating other durvalumab combinations may be added based on emerging preclinical and clinical data. The primary endpoint is objective response per RECIST v1.1 with monotherapy and combination therapy. Secondary endpoints include safety, efficacy (duration of response, disease control, PFS, 12-month PFS rate, OS), pharmacokinetics and immunogenicity. The COAST study is open for accrual with an estimated total target enrollment of up to 60 patients per treatment arm.
IntroductionAddictive behaviors and suicide have important risks that need to be explored for any patient followed at the department of psychiatry, possibly endangering his vital and psychosocial prognosis.ObjectivesOur study aims to identify the link between addictive behavior and suicidal behavior in patients followed at the psychiatry department at the regional hospital of Gabes.MethodsWe conducted a cross-sectional, descriptive and analytical study carried out on a clinical population who consult in the psychiatry department in the Gabes’s regional hospital during the period from January 1st, 2020 to September 30, 2020.Sociodemographic and clinical data of the patients as well as their personal and family history were assessed. The evaluation of psychopathological disorders was carried out according to the diagnostic criteria of DSM-5. Suicide Behaviors Questionnaire (SBQ) was used for suicide risk assessment. Fagerstrom questionnaire in its validated French version was used to assess the of nicotine dependence. The exploration of childhood physical and emotional trauma was carried out by the Childhood Trauma Questionnaire (CTQ) scale. Data were analysed using the software SPSS.Results100patients were included. The mean age was 45.5years. TableI: Breakdown of addictive behavior and suicide attempts by gender. TableII: Common vulnerability factors between addictive behavior and suicidalityThe analytical study showed that suicide attempts were correlated with addictive behaviors (p = 0.03) and that suicidal recurrence was correlated with addictive behaviors (p = 0.01).ConclusionsSuicidal behavior in patients followed in psychiatry is closely linked to addictive behavior, hence the importance of early management.
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