Introduction: Aortic thromboembolism is relatively common among patients following cardiovascular procedures and trauma. The abdominal aorta is the most common site for thrombosis, especially its distal portion. Based on the Virchow triad, thrombosis is caused by an imbalance among endothelium, blood flow, and coagulation. Inherited or acquired hypercoagulable states play a key role in thrombus formation in both the arteria and venous system. Elevated levels of C-reactive protein, homocysteine and lipoprotein (a) are more likely to be involved with arterial thrombus. Antiphospholipid antibodies are associated with both venous and arterial thromboembolic events. The advent of new radiologic modalities, with more noninvasive techniques, has allowed for early diagnostics and treatment of these entities, in neonatal population. Case Report: We report the case of five days newborn, with a sepsis history due to foeto-maternal infection, who needed an umbilical catheter for monitoring. Three days later, he presented with distal ischemia an abolition of femoral artery pulses in front of that we conducted a Doppler ultrasound (US) and a computed tomography (CT) angiography, which demonstrated an inframesenteric aorta thrombosis which extended to the iliac axes. No surgery was necessary, and an anti-thrombin
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