BACKGROUNDThe study was aimed to compare the pattern of lipid profile among young smokers and nonsmokers.
MATERIALS AND METHODSProspective study was carried out to compare the pattern of lipid profile among young smokers and nonsmokers aged between 20-30 years. A total of 100 patients were enrolled in our study in which 50 were smokers and 50 nonsmokers. Patient relevant data was collected from inpatient and outpatient department of medicine, RMMCH. Serum lipid profile was analysed in all the subjects.
RESULTSThe mean±SD of serum total cholesterol was 183±37.5/165.32±17.38 mg/dL (smokers/nonsmokers), the mean ± SD of serum triglyceride is 173.68±31.08/141.1±13.27 mg/dL (smokers/nonsmokers), the mean±SD of serum LDL-cholesterol was 114±28.8/107.46±22.04 mg/dL (smokers/nonsmokers), levels in smokers was higher compared to levels in control group (nonsmokers). The mean ± SD of serum of HDL-cholesterol levels in smokers was 48.6±5.33/49.7±3.54 mg/dL (smokers/nonsmokers) which was lower compared to levels in control group.
CONCLUSIONSmoking causes alteration in lipid profile and increased risk of cardiovascular disease.
A rare form of hypertrophic cardiomyopathy predominantly involving the left ventricular apex is called as Apical Hypertrophic Cardiomyopathy (AHCM). This variant, more commonly seen in Japanese populations had been detected in a middle-aged SouthIndian man by 2D echocardiography.
A 63 years-old male patient diagnosed with relapsed / refractory multiple myeloma who requires Daratumumab as a part of treatment in the eighth line of management. The flow cytometry showed 63.5% of Plasma Cells with expression of CD38+. Daratumumab + Lenalidomide + Dexamethasone regimen was ordered. After 4 cycles o f treatment, an evaluation o f response was performed a n d documented partial r e s p o n s e . Nevertheless, flow cytometry revealed 4.8% of abnormal Plasma Cells in bone marrow CD38 Negative.
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