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Lung cancer is a common disease and the leading cause of cancer-related mortality, with non-small cell lung cancer (NSCLC) accounting for the majority of cases. Following diagnosis of lung cancer, accurate staging is essential to guide clinical management and inform prognosis. Positron emission tomography (PET) in conjunction with computed tomography (CT)-as PET-CT has developed as an important tool in the multi-disciplinary management of lung cancer. This article will review the current evidence for the role of F-fluorodeoxyglucose (FDG) PET-CT in NSCLC diagnosis, staging, response assessment and follow up.

We reviewed all patients over a 3-year period with documented aneurysms of the posterior cerebral circulation, and re-examined the angiograms of 103 patients. There were 9 cases of fenestration of the basilar artery, all associated with aneurysms of the basilar artery. In 6, the aneurysm arose at the site of the fenestration. We believe that the presence of a fenestration predisposes to aneurysm formation, due to the combination of the resulting alteration in flow characteristics and the presence of a defect in the media of the vessel.

Contrary to ACCP guidelines, we found that ventilation scintigraphy alone provided the best correlation between the predicted and actual postoperative values and recommend its use to predict postoperative lung function. However, scintigraphic techniques may underestimate postoperative lung function, so caution is required before unnecessarily preventing a patient from undergoing surgery that offers a potential cure.

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Objective: To investigate CT findings in patients with pathologically proven mesenteric ischaemia postcardiopulmonary bypass surgery and compare them with the control group of patients without ischaemia. Methods: 68 patients were identified by a search of local surgical and pathological databases; these patients met the inclusion criteria of a laparotomy within 1 month of a procedure requiring cardiopulmonary bypass and a CT abdomen/pelvis within 1 week of the pathological diagnosis. Two radiologists independently reviewed the studies, evaluating 17 separate findings relating to the bowel, the vasculature or other structures; consensus was subsequently reached. The diagnostic value of CT findings was assessed using logistic regression. Results: 52 of 68 patients had pathologically proven ischaemia. Portal venous gas, mesenteric venous gas and small bowel faeces sign all had specificities of .0.94 for ischaemia but low sensitivity (,0.27). Differential mural enhancement had high sensitivity (0.92) but poor specificity (0.50). The combination of pneumatosis, bowel loop dilatation and differential mural enhancement predicted bowel ischaemia with a probability of 98%. The hardest signs to interpret based on poor interreader kappa agreement were bowel wall thinning, mesenteric stranding and differential mural enhancement. Conclusion: A combination of CT signs was predictive of ischaemic bowel; however, the more specific findings lacked sensitivity. If clinical suspicion is high for bowel ischaemia, prompt surgical intervention is warranted, regardless of CT findings. Advances in knowledge: Arterial occlusion was uncommon and venous occlusion was not present, which is supportive of a predominantly non-occlusive aetiology for ischaemia in this patient group.

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Radiographic staff in a regional cardiothoracic centre were asked to assess all pre- and post-operative chest radiographs over a 6-month period. Radiographs showing new, acute changes were noted and a red dot placed on the film. Medical staff were notified of radiographs with red dots, and these were subsequently reported by radiologists. Using reports by radiologists as the gold standard, an audit was performed of the radiographers' accuracy in identifying new abnormalities. The absence of a necessary red dot as well as inappropriate use were noted. To enhance the accuracy of radiograph interpretation, a series of lectures on the chest radiograph and a protocol for red dot use were developed by senior radiologists. During this 6-month period 8614 chest radiographs were taken; red dots were applied to 464 (5%). These red dots were considered incorrect in 100 radiographs. Radiographers misinterpreted or missed potentially important changes in 38 of the remaining 8150 radiographs without red dots (sensitivity and specificity of 90% and 99%, respectively). Radiographers appeared to err on the side of caution when confronted with an abnormal chest radiograph, especially when previous radiographs and reports were unavailable. This resulted is a relatively high false positive rate. Future audits will show whether this rate can be reduced by continued training. Subtle interpretation is crucial to distinguish between an abnormal chest radiograph needing urgent medical attention and an abnormal chest radiograph with normal post-operative changes. The opinion of the experienced and trained radiographer is immediate and may be invaluable to the diagnostic care of the patient.