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An imaging system has been developed based on pulses of Terahertz (THz) radiation generated and detected using all-optical effects accessed by irradiating semiconductors with ultrafast (fs-ps) pulses of visible laser light. This technique, commonly referred to as T-Ray Imaging or THz Pulse Imaging (TPI), holds enormous promise for certain aspects of medical imaging. We have conducted an initial survey of possible medical applications of TPI and demonstrated that TPI images show good contrast between different animal tissue types (muscle, fat, kidney, skin, cartilage). Moreover, the diagnostic power of TPI has been elucidated by the spectra available at each pixel in the image, which are markedly different for the different tissue types. This suggests that the spectral information inherent in TPI might be used to identify the type of soft and hard tissue at each pixel in an image and provide other diagnostic information not afforded by conventional imaging techniques.Preliminary TPI studies ofpork skin show that 3D tomographic imaging ofthe skin surface and thickness is possible, and data from experiments on models of the human dermis are presented which demonstrate that different constituents of skin have different refractive indices. Lastly, we present the first THz image of human tissue, namely an extracted tooth. The time of flight of THz pulses through the tooth allows the thickness of the enamel to be determined, and is used to create an image showing the enamel and dentine regions. Absorption of THz pulses in the tooth allows the pulp cavity region to be identified. Initial evidence strongly suggests that TPI may be used to provide valuable diagnostic information pertaining to the enamel, dentine, and the pulp cavity.

We present a theoretical treatment of surface-field THz generation in semiconductors, which explains the power enhancement observed when a magnetic field is applied. Our model consists of two parts: a Monte Carlo simulation of the dynamics of carriers generated by a subpicosecond optical pulse, and a calculation of the resulting THz radiation emitted through the semiconductor surface. The magnetic field deflects the motion of the carriers, producing a component of the THz dipole parallel to the surface. This causes the power transmitted through the surface to be increased by more than one order of magnitude.

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