Introduction:Cerebral venous sinus thrombosis (CVST) is an unusual cause of stroke with potentially serious consequences. This study was designed to investigate the clinical and neuroimaging features in patients with CVST and to analyze the predictors of brain parenchymal lesions.Materials and Methods:A retrospective study of 181 patients with CVST was conducted in a tertiary care hospital.Results:Of 181 patients (age range 14–96 years, mean age: 34.64 ± 14.66 years), 121 were female (66.9%). Most of the patients were in their third decade of life. Headache (47.51%) was the most common clinical presentation followed by seizures (24.31%). Transverse sinus (TS) (77.9%) was the most common site of venous sinus thrombosis. Brain parenchymal lesions were present in 63%, and each patient had subarachnoid and intraventricular hemorrhage. Hemorrhagic venous infarct was the most common brain parenchymal lesion (37.57%). Frontal region (25.4%) was the most common site of brain parenchymal lesions followed by frontoparietal region (21.9%). Women were more likely to have brain parenchymal lesions (72.4%, P = 0.034). Headache was the most common clinical presentation in patients without brain parenchymal lesions while seizures with brain parenchymal lesions. Straight sinus thrombosis was more likely to be associated with brain parenchymal lesions (P = 0.009).Conclusion:CVST presents in young and more commonly in females. TS was the most common site of venous sinus thrombosis. Female gender, seizures, altered sensorium and focal neurological deficit at presentation, and straight sinus thrombosis were more likely associated with the presence of brain parenchymal lesions.
Aims
This study was designed to assess the oral alterations and oral health related quality of life (OHRQoL) in patients undergoing chemotherapy for malignancies other than oral cancer.
Methods and results
Oral alterations were studied by careful clinical examination prior to and at the end of three cycles of chemotherapy in 100 patients. OHRQoL was assessed by oral health impact profile (OHIP)‐14 questionnaire. Fifty‐four patients developed oral complications among which oral mucositis and pigmentation were the most commonly observed. OHRQoL was hampered in all patients as indicated by higher postchemotherapy scores as compared to prechemotherapy scores (P < .0001). Postchemotherapy scores were higher for patients who developed visible oral changes as compared to those who did not (P = .001). There was a weak positive correlation between the number of oral alterations and postchemotherapy scores for OHRQoL.
Conclusions
Our study emphasizes the role of oral physicians in the healthcare team delivering chemotherapeutic treatment as regular oral examination, and timely symptomatic treatment is important for the overall well‐being of the patient.
Introduction:The modern-day lifestyle and industrialization has led to the deficiency of sunshine vitamin, i.e., vitamin D, in all age groups. Vitamin D deficiency has its implications in almost each system and has widespread manifestation. This deficiency has far more severe outcomes when associated with diabetes.
Aim:To evaluate vitamin D level in type II diabetes patients.
Materials and methods:One hundred diabetic patients will be screened for serum 25-hydroxyvitamin D level by enzymelinked immunosorbent assay technique and the results will be statistically analyzed.
Results:In our study, vitamin D was deficient in 42%, insufficient in 40%, and normal in 18% cases. Deficiency was seen more in female diabetics. This study has significant correlation with glycated hemoglobin (HbA1c) level and vitamin D level, i.e., as HbA1c increased, so is the vitamin D deficiency.
Conclusion:Vitamin D was deficient in more than 80% of diabetic patients. Therefore, all diabetic patients should be investigated for vitamin D level.
F-18 FDG PET-CT is an establish modality for staging of cervical cancer. The high uptake value in PET with no evidence of necrosis in CECT is generally understood malignant pathology in known cancer patients. A 47 year-old-female with cervix carcinoma underwent staging FDG PET-CT. It showed FDG avid primary lesion in cervix with FDG avid pelvic, retroperitoneal, mediastinal and supraclavicular lymph nodes. USG guided FNA from the supraclavicular lymph node revealed tuberculosis. Now patient scheduled for ATT and chemotherapy.
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