Exposure to cadmium (Cd) has harmful effects on the liver and kidney. Resveratrol (RES) is an herbal substance that functions as a protective mediator. This study aimed to investigate the effects of RES on the histology of liver and kidney in Cd-exposed mice. Male mice were divided into 4 groups daily receiving normal saline (1 mL normal saline/d), Cd (1 mg/kg/d), RES (20 mg/kg/d), and Cd plus RES, respectively. After 4 weeks, the liver and kidney components were evaluated using stereological methods. The total volume and number of hepatocytes, and volume of fibrous tissue were respectively increased by 34%, 58%, and a 3-fold in the Cd-exposed mice in comparison to the control animals (P＜0.03). On the other hand, the volume of the main vasculature (sinusoids and central veins) was decreased by 36% in the Cd group compared to the control mice (P＜0.03). Considering the kidney, the results showed a 3-fold increase in the total glomeruli volume and a 7-fold increase in fibrous tissue in the Cd-treated group compared to the control mice (P＜0.03). After Cd treatment, a 32% reduction was observed in the volume and length of the proximal and distal convoluted tubules. RES-treatment alone did not induce any structural changes. In comparison to the Cd group, an increase in the normal components of the liver and kidney and a decrease in the formation of the fibrous and degenerated tissues were observed in the Cd+RES-treated mice (P＜0.03).

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Introduction:Anxiety is a kind of agitation and concern stemming from the feeling of threat or hazard in human soul.Materials and Methods:This study was monitored by triangular sequential analysis test.The samples consisted of 110 patients undergoing coronary artery angiography among whom 55 patients were randomly chosen to be allocated in the control group and 55 patients in experimental group.The demographic questionnaire,Spilburge's stat-trait anxiety inventory and digital indicator were used to collecting data.About one hour before angiography, the demographic past of the questionnaire was completed by the participants in both groups.Then sooting and no words music was played for the experimental group for 15 minutes.Results:The results of this study indicated that after the entrance of 80 patients in the fourth interim analysis in this study(41 in the test group and 39 in the control group), the clinical trial stopped in the interests of the test group(p=0.009 triangular test).the rate of anxiety stat and trait, systolic and diastolic blood pressure and respiratory rate of the test group after music intervention indicated statistically significant difference in contrast to the control group, based on the results the analysis of covariance test. But the difference between the heart rate in these two groups was not statistically significant)p=0.174).Conclusion:The results obtained indicated the effect of music on coronary artery angiography anxiety.Therefor, it can be concluded that listening to music may be an assisting treatment for anxiety and its resulting physiological signs.