Among young children in a developing country, we found evidence to support the hypothesis of a protective effect of H. pylori infection on the risk of allergic disease. Further investigation of the mechanism of this effect is therefore of potential therapeutic and preventive value.

Background:The care of patients with severe mental disorder in Ethiopia remains centralized in the capital city. Objective: To assess pattern of psychiatric admission and its implication for service provision. Methods: A descriptive analysis of one-year admission data was undertaken from the only psychiatric hospital in Ethiopia. Results:The annual age-sex standardized admission rate was 4 per 100 000 (n=1564). Two-thirds of the patients came from Addis Ababa and the immediate surrounding areas. Nearly three-quarters were men, and aged 30 years or younger. Schizophrenia and bipolar disorder were the top two discharge diagnoses. IntroductionThe provision of adequate, fair and equitable care for patients in the developing world, particularly in subSaharan Africa is one of the greatest challenges of the 21 st century health system. The "unfinished agenda" of infectious diseases (1) remains a legitimate priority, but the burden from psychiatric disorders and other chronic diseases continues to grow unchecked. These concerns are compounded by un-moderated population growth, continuing economic constraints and unparalleled socioeconomic and geo-political changes.

An outbreak of cholera involving 161 culture-positive cases of biotype El-Tor Serotype Ogawa occurred in the Gaza Strip in the summer and autumn of 1981. The signs and symptoms of the disease were mild to moderate in two thirds of the cases. In many of them the disease was so mild that the patients did not realize they had cholera. Another outstanding feature of the disease was the high percentage of family clustering. From constant monitoring of water, sewage, and vegetables we were unable to show that they played any part in the transmission. A case control study which specifically investigated these items showed no differences between cases and controls. Epidemiological investigation indicated that the disease was probably introduced into the area by a visitor from Jordan, where an epidemic was in progress. The first spread followed a wedding party and seems to have been caused by ingestion of contaminated soft drinks. Subsequent spread was probably caused mainly by carriers who were either asymptomatic or very mild cases. The actual transmission seems to have occurred from person to person, by food contamination, or by both. The authors believe, therefore, that the transmission of El-Tor cholera has many features in common with other bacterial diseases that are transmitted by the faecal-oral route.

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