ChemInform Abstract The β-aroylpropionic acids (I) react with thiophene-2-carboxaldehyde (II) to give the butenolides (IIIa) which are transformed into the 5-oxopyrrolines (IIIb) and into the acrylic acid hydrazides (VI). Upon treatment with acid, the hydrazides (VI) are cyclized, forming the pyridazinones (VII). The compounds are tested for their activity against bacteria and yeasts.
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