التأثیرات العلاجیة المحتملة لبذور الشیا وعباد الشمس على الفئران التی یتم تغذیتها على غذاء عالی فی الدهون

Abstract

The present study was conducted to investigate the potential therapeutic effects of chia, sunflower seeds, and their mixture(CS, SFS and Mix) as rich sources of ALA in different concentrations (2.5 and 5%) on rats fed high fat diet. Forty-eight female albino rats weighting (150±10 g) were divided in eight equal groups(n=6), the first group: Fed on basal diet. All remaining rats (n=42) fed on high fat diet (HFD) and classified into the follow Group 2: positive control group. Groups 3 and 4: Fed on HFD +2.5 and 5 % CS, respectively. Groups 5 and 6: Fed on HFD + SFS, respectively. Finally, groups 7 and 8: Fed on HFD +2.5 and 5%Mix, respectively. The experiment lasted for 28 days. The best results for liver enzymes were recorded in group four (5%CS) with percent of change 40.00,48.75 and 22.96 for GPT, GOT and ALP, respectively. While, the best values of LDLc, serum glucose level and kidney function were recorded in group eight (5% Mix) where there was a significant reduction p ≤ 0.05 with percent of change 60.00 and 51.7 % for LDLc and serum glucose level & 61.76 and 52.00 % for urea and creatinine. In conclusion, this study recommended the incorporation of CS and SFS as functional foods in diet daily routine to provide more effective health benefits.