2017
DOI: 10.22625/2072-6732-2017-9-4-5-13
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Роль Тромбоцитов В Патогенезе Бактериальных Инфекций

Abstract: Резюме Abstract In recent years, a critical mass of information has accumulated, which has made it possible to equate platelets to the cells of innate immunity, which ensures the initiation of inflammation and the reactions of innate immunity. In the presented review platelets were examined from the point of view of antibacterial immune reactions. Mechanisms that allow platelets to recognize bacteria and their soluble products as characteristic of immune cells (via TLR2, TLR4, TLR7 and TLR9, FcγRIIa and recep… Show more

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Cited by 5 publications
(4 citation statements)
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References 15 publications
(20 reference statements)
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“…Also, one of the most important scientific and practical issues is the study of the agricultural sector, the use of cartographic support methods in the analysis [1,2]. In this regard, the study of agricultural, natural and socioeconomic problems related to economic development in the United States, Russia, Ukraine, Germany, China, Vietnam and other developed countries, including the use of electronic agricultural maps to provide reliable information about the region special attention is paid to current scientific and practical issues [2,4,6].…”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“…Also, one of the most important scientific and practical issues is the study of the agricultural sector, the use of cartographic support methods in the analysis [1,2]. In this regard, the study of agricultural, natural and socioeconomic problems related to economic development in the United States, Russia, Ukraine, Germany, China, Vietnam and other developed countries, including the use of electronic agricultural maps to provide reliable information about the region special attention is paid to current scientific and practical issues [2,4,6].…”
Section: Introductionmentioning
confidence: 99%
“…Analysis of the existing scientific literature in the field shows that scientific research has been conducted in Uzbekistan, along with foreign scientists, on the cartographic study and support of problems related to the location and development of agriculture as a basic sector of the economy. Consequently, the theoretical and methodological bases of agricultural mapping have been studied by scientists from foreign and Commonwealth countries [4,9,11,16].…”
Section: Introductionmentioning
confidence: 99%
“…Причем одна и та же бактерия может инициировать оба пути активации [13]. После активации бактериями тромбоциты агрегируют не всегда, выпуская в таких случаях содержимое δ-гранул и стимулируя воспалительную реакцию за счет привлечения нейтрофилов к формированию внеклеточных ловушек (neutrophil extracellular trap -NET) [14]. В ряде случаев при бактериемии может происходить диссеминированная активация тромбоцитов, которая приводит к нарушениям микроциркуляции и высвобождению медиаторов воспаления, способствуя развитию синдрома полиорганной дисфункции (СПОД) [15].…”
Section: Introductionunclassified
“…Moreover, the same bacteria can initiate both activation pathways [13]. After activation by bacteria, platelets do not always aggregate, releasing the contents of δ-granules and stimulating the inflammatory reaction by recruiting neutrophils to form neutrophil extracellular traps (NET) [14]. In some cases of bacteremia, disseminated platelet activation may occur, which leads to microcirculatory disorders and release of inflammatory mediators, contributing to multiple organ failure syndrome (MOFS) [15].…”
Section: Introductionmentioning
confidence: 99%