Определение Соматических Мутаций В Гене EZH2 И Оценка Их Прогностической Значимости При Фолликулярной Лимфоме 1–3А Цитологического Типа
Екатерина Сергеевна Нестерова,
Н. А. Северина,
Б. В. Бидерман
et al.
Abstract:Aim. To determine the incidence and prognostic value of mutations in exon 16 of EZH2 as well as those of polymorphism с.1582-21А>G (rs2072407) in EZH2 in patients with follicular lymphoma (FL) grades 1–3А in relation to morphologic and cytogenetic tumor characteristics.
Materials & Methods. The prospective cohort study conducted by the National Research Center for Hematology from January 2017 to April 2021 enrolled 80 patients with newly diagnosed FL grades 1/2 and 3А. The median follow-up was 53 … Show more
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