МЕХАНИЗМЫ ФОРМИРОВАНИЯ, РЕГУЛЯЦИИ И АДРЕСНОЙ КОРРЕКЦИИ ИММУННЫХ РАССТРОЙСТВ, "Успехи Современной Биологии"

Земсков, А. М.; Земсков, В.М.; Земскова, В. А.

doi:10.7868/s0042132418040051

Cited by 2 publications

(3 citation statements)

References 4 publications

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“…Чаще всего последовательная альтернативность иммунных реакций является необходимым условием устранения расстройств реактивности организма [7,16,17].…”

Section: альтернативность иммунных реакцийunclassified

“…В остром периоде патологических процессов отмечается выраженная вариабельность различных компенсаторных реакций. На стадии ремиссии или выздоровления изменчивость параметров снижается и проявляется интеграция реагирования [22]. Так, у пациентов с глубокой пиодермией в остром периоде заболевания установлено изменение сгруппированных клинических, бактериологических, гематологических, метаболических параметров 2-го ранга (в пределах 33-66%).…”

Section: альтернативность иммунных реакцийunclassified

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Immune reactions as induction factors and correction of the pathology

Zemskov¹,

Земсков

Neymann³

et al. 2022

Medicinskij sovet

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On clinical models of infectious, somatic, malignant, and other diseases, the ability of immune responses to induce pathological processes due to competition, “pathogenicity”, hypersensitivity, and insufficiency has been shown. We are talking about the competitiveness of antibacterial and antiviral immunity, when the deployment of cellular and humoral immune responses weaken both defense mechanisms, competition of allergy and immune deficiency, which aggravates and modifies it, and antiviral immunity often induces a number of pathological conditions of the body. This is due to the inability of antiviral antibodies to completely inactivate the antireceptor structures of virions, interact with them without changing their function, and even stimulate a viral infection, induce autoimmune reactions. The protective system of interferons, which often cause side reactions, is also faulty. In the body, immunopathological reactions develop, manifested by immediate and delayed hypersensitivity, which have alternative properties – protective and damaging and autoimmune reactions, mainly with a negative effect. The mechanisms of the processes are discussed in detail in the review. The “inferiority” of immune reactions, respectively, cellular, humoral, phagocytic links, incomplete consistency of anticancer immunity, virus-induced immunodeficiencies are comprehensively covered. Such “alternativeness” of the considered immune reactions, at the same time, turns out to be a necessary condition for eliminating the emerging disorders of the organism’s reactivity. These include specificity and non-specificity, stimulation and suppression, variability and integration of immune responses. At the same time, immunoregulatory reactions are individual and interrelated, develop regionally and systemically and provide degradation of exogenous and endogenous objects and immune activation. All these aspects are discussed in detail in the review.

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Section: альтернативность иммунных реакцийunclassified

Immune reactions as induction factors and correction of the pathology

Zemskov¹,

Земсков

Neymann³

et al. 2022

Medicinskij sovet

View full text Add to dashboard Cite

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“…Также за последние годы было сформировано понятие феномена метаболического иммунитета [12] и признано функциональное единство иммунологической и центральной нервной систем [13,14]. Вышеуказанные факторы приводят к мысли о необходимости дальнейшего научного взгляда в направлении возможной связи носи-тельства вирусов герпесной группы и течения тревоги и депрессии.…”

Section: Introductionunclassified

Impact of antibodies to herpesviruses on clinical and laboratorial parameters among patients with mixed anxiety and depressive disorder

Bakuleva,

Zemskova,

Choporov

et al. 2023

Immunopathol Allergol Infectol

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Воронежский областной клинический психоневрологический диспансер, Воронеж 2 Воронежский государственный медицинский университет им. Н.Н. Бурденко, Воронеж Impact of antibodies to herpesviruses on clinical and laboratorial parameters among patients with mixed anxiety and depressive disorder

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МЕХАНИЗМЫ ФОРМИРОВАНИЯ, РЕГУЛЯЦИИ И АДРЕСНОЙ КОРРЕКЦИИ ИММУННЫХ РАССТРОЙСТВ, "Успехи Современной Биологии"

Cited by 2 publications

References 4 publications

Immune reactions as induction factors and correction of the pathology

Immune reactions as induction factors and correction of the pathology

Impact of antibodies to herpesviruses on clinical and laboratorial parameters among patients with mixed anxiety and depressive disorder

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