Маркеры Субклинического Поражения Артерий В Выборке Жителей Санкт-Петербурга (По Данным Эссе-Рф)

Сайгидовна, Алиева Асият; Анатольевна, Бояринова Мария; Викторовна, Могучая Екатерина; Павловна, Колесова Екатерина; Юрьевна, Васильева Елена; Николаевич, Солнцев Владислав; Петровна, Ротарь Оксана; Олеговна, Конради Александра

doi:10.18705/1607-419x-2015-21-3-241-251

Cited by 4 publications

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“…Основные характеристики выборки описаны ранее в нашей публикации [6]. Доля лиц с АГ, гипертриглицеридемией и повышенным уровнем гликемии была выше среди мужчин, в то время как женщины чаще имели ожирение по критерию окружности талии (ОТ) и более высокий уровень общего холестерина.…”

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Hormonal determinants of prehypertension in a random sample of St. Petersburg residents: data from the ESSE-RF study

et al. 2021

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Aim. To determine the association of prehypertension (PHTN) with cardiometabolic and hormonal factors in a population sample of St. Petersburg residents.Material and methods. As part of the ESSE-RF epidemiological study, a random sample of 1600 residents of St. Petersburg at the age of 25-64 was examined. All participants signed informed consent and completed the questionnaires. Anthropometry, fasting venous blood sampling, blood pressure (BP) measurements were performed. BP was measured by the OMRON BP monitor (Japan) twice on the right hand in a sitting position. Mean BP was calculated. Respondents, depending on the BP level and availability of antihypertensive therapy, were divided into 3 groups: optimal BP (<120/80 mm Hg), PHTN (120-139/80-89 mm Hg) and HTN (≥140/90 mm Hg or antihypertensive therapy). Blood levels of insulin, N-terminal pro-brain natriuretic peptide (NT-proBNP), thyroid-stimulating hormone, C-reactive protein (CRP), morning cortisol, leptin, adiponectin were assessed. The insulin resistance index was calculated using the Homeostatic Model Assessment (HOMA) according to the following equation: glucose (mmol/l) × insulin (μIU/ml))÷22,5. Mathematical and statistical data analysis was carried out using the SPSS Statistics 26 program.Results. The data from 1591 participants were analyzed. Among the surveyed persons, women predominated (n=1025; 64,4%). With BP increase from optimal to PHTN, HTN, the levels of CRP, insulin, HOMA-IR and leptin increases in male and female respondents. In addition, there is an increased prevalence of hyperinsulinemia and insulin resistance in the female population. Multiple logistic regression, adjusted for sex, age, obesity ( body mass index ≥30 kg/m2) and waist circumference (≥102 cm for men and 88 cm for women), revealed associations of PHTN with an increase in insulin >173,0 pmol/L (2,99 [1,22; 7,36], p=0,017), HOMA-IR >2,9 (2,12 [1,42; 3,19], p<0,0001) and associations of HTN with an increase in insulin >173,0 pmol/L (2,14 [1,30; 3,54], p=0,003), HOMA-IR >2,9 (1,83 [1,39; 2,42 ], p536 nmol/L (1,59 [1,25; 2,05], p125 pg/ml (2,05 [1,32; 3,20], p=0,002).Conclusion. In a random sample of St. Petersburg residents, the presence of hyperinsulinemia increases the risk of PHTN and insulin resistance by 3 and 2 times, respectively.

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Hormonal determinants of prehypertension in a random sample of St. Petersburg residents: data from the ESSE-RF study

et al. 2021

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Meta-Analysis of Randomized Clinical Trials on the Speed of Pulse Wave Propagation

Gharamyan

2023

BIOPHYSICS

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Meta-analysis of randomized clinical trials on the speed of pulse wave propagation

Gharamyan

2023

Biofizika

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This paper presents a theoretical analysis of the literature on the speed of pulse wave propagation using a combination of ECG and PPG signals. The diagnostic value of pulse wave velocity in medical practice is use of this indicator for non-invasive measurement of blood pressure and also for determination of arterial stiffness. Some studies have shown an association of pulse wave velocity with risk factors for cardiovascular disease. The speed of pulse wave propagation is an early marker and predictor of cardiovascular risk both in individuals with normal blood pressure and people with hypertension and is used as the "gold standard" for assessing arterial stiffness; however, the question about accuracy and automation of the measurement of the speed of pulse wave propagation still remains to be answered.

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Маркеры Субклинического Поражения Артерий В Выборке Жителей Санкт-Петербурга (По Данным Эссе-Рф)

Cited by 4 publications

References 0 publications

Hormonal determinants of prehypertension in a random sample of St. Petersburg residents: data from the ESSE-RF study

Hormonal determinants of prehypertension in a random sample of St. Petersburg residents: data from the ESSE-RF study

Meta-Analysis of Randomized Clinical Trials on the Speed of Pulse Wave Propagation

Meta-analysis of randomized clinical trials on the speed of pulse wave propagation

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