Abstract:In this study, quantitative analysis of inflammatory effectors--mast cells and eosinophils--in derma of people of different ages is performed. The study shows that mast cell quantity in derma increases with age. Eosinophils are rarely observed in human dermis. There are no age-correlated changes of dermal eosinophils quantity observed. Age-correlated dermal fibroblast quantity is established. PCNA+ fibroblast percentage demonstrating their proliferative pool also reliably decreases with age. Results of correla… Show more
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