Вміст Ліпідів У Сироватці Крові Корів За Спонтанного Інфікування Вірусом Лейкозу Великої Рогатої Худоби

Abstract

Lipids take part in the biological cycle of retroviruses and regulation of their expression. In particular, in the processes associated with the interaction with the lipid bilayer of the host cell (virus penetration into the cell), and budding of newly synthesized viral particles. To study the effect bovine leukemia virus on lipid metabolism in the host organism is very important for veterinary medicine, because of its effect on animal blood system. At the same time, changes in the blood system of lactating cows have a significant impact on the biochemical indicators of quantitative composition of the milk and therefore its quality, nutritional value and safety for consumers. Investigated the lipid composition of blood serum of cattle spontaneous infected with the virus leukemia. For study was formed by two groups of cows black–and–white breed in 3 years of age on 3 – 4 months of lactation, body weight were 400 – 450 kg, 6 animals in each. In the first (control) group was clinically healthy animals, free from bovine leukemia virus (according to the RID, ELISA and PCR studies), the second (experimental) was animals which infected by virus bovine leukemia. Established that in the infected animals significantly increases the content of total phospholipid by 6.0%, total and esterified cholesterol by 4.3 and 4.2%, respectively. Thus, the correlation of total cholesterol to total phospholipids was unchanged in both groups of animals. Also, in the blood serum of cows research groups noted increase of free fatty acids content by 83.3%. Thus, at the spontaneous infection the bovine leukemia virus in animals is a disturbance qualitative and quantitative composition of blood serum lipids owing to disturbance of synthetic processes in liver, caused by the necessity in the plastic material for build lipid layer of shell pathogen.