η6-(2-phenoxyethanol) ruthenium(II)-complexes of 2,2′-bipyridine and its derivatives: Solution speciation and kinetic behaviour

Abstract

pH values, the slow oxidation of the Ru II centre takes place as well leading to the partial loss of the arene moiety. The rate of these processes depends on the pH and its maximum was found at pH 8-9. Additionally the chlorido/aqua co-ligand exchange processes of the [Ru II ( 6 -(2-phenoxyethanol))(L)Cl] + species were also monitored and only ~5% of the chlorido ligand was found to be replaced by water in 0.1 M chloride ion containing aqueous solutions at pH 5.

Binding mechanisms of half-sandwich Rh(III) and Ru(II) arene complexes on human serum albumin: a comparative study

“…Notably, the recorded spectra did not indicate the loss of p -cymene ligand from the Ru(II) center (see details in Refs. [72, 73]). More detailed qualitative information can be obtained on the albumin-bound form of RhCp* (Fig.…”

Methyl-cyclopentadienyl Ruthenium Compounds with 2,2′-Bipyridine Derivatives Display Strong Anticancer Activity and Multidrug Resistance Potential

“…Stability in a physiological like media prior to in vitro evaluation of metallodrugs is a very important issue when assessing the mettallodrugs' biological activity. 36 In this context, all complexes were tested for their aqueous stability over time using DMSO and culture cellular media DMEM by UV−vis spectroscopy. DMSO was used to dissolve the compounds because they are not completely soluble in the DMEM media.…”