ε-Poly-L-lysine-protected Ti3C2 MXene quantum dots with high quantum yield for fluorometric determination of cytochrome c and trypsin

Lyu, Mingsheng; Zhou, Ji; He, Yu; Cai, Zhaoxia; Ge, Yili; Zhou, Jiangang; Song, Guang

doi:10.1007/s00604-019-3945-0

Cited by 56 publications

(37 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…According to 3s/ slope, the detection limit of Try was 8.08 ng mL À1 , which was lower than that of the as-reported uorescent methods according to the active group-modied signal probes. 26,33,34 As listed in Table S1 † and compared with other published methods for TRY, this method has a good linear relationship with an acceptable LOD for the detection of TRY. Under the optimal conditions, the method has the advantages of convenience, efficiency, sensitivity and a simple operation.…”

Section: Assay Of Trymentioning

confidence: 86%

“…Herein, negatively charged CQDs, fabricated from a simple melting operation, were applied as the sensing probe for Try detection without any complex surface functionalization or conjugation and compared with other reported quantum dots, 26 as shown in Scheme 1. Using Pro as the selective enzymatic substrate for Try, the integration of the prepared CQDs and Pro induce them to assemble and form an aggregation-caused quenching system of CQDs and Pro (CQDs/Pro) via electrostatic interaction.…”

mentioning

confidence: 99%

See 1 more Smart Citation

A simple fluorescence assay for trypsin through a protamine-induced carbon quantum dot-quenching aggregation platform

et al. 2020

View full text Add to dashboard Cite

show abstract

Section: Assay Of Trymentioning

confidence: 86%

mentioning

confidence: 99%

A simple fluorescence assay for trypsin through a protamine-induced carbon quantum dot-quenching aggregation platform

et al. 2020

View full text Add to dashboard Cite

show abstract

“…The hydroxyl groups on the surface of MXene provide the possibility to introduce some functional groups via esterification reaction, such as amine groups [65][66][67] and long-chain alkanes. [68] It could increase the interactions between MXene and polymer and tune the surface chemistry of MXene.…”

Section: Binding Through Esterificationmentioning

confidence: 99%

Preparation Strategies and Applications of MXene‐Polymer Composites: A Review

Sun

Zhang

et al. 2021

Macromol. Rapid Commun.

View full text Add to dashboard Cite

As a new member of the 2D material family, MXene integrates high metallic conductivity and hydrophilic property simultaneously. It shows tremendous potential in fields of energy storage, sensing, electromagnetic shielding, and so forth. Due to the abundant surface functional groups, the physical and chemical properties of MXene can be tuned by the formation of MXene-polymer composites. The introduction of polymers can expand the interlayer spacing, reduce the distance of ion/electron transport, improve the surface hydrophilicity, and thus guide the assembly of MXene-polymer structures. Herein, the preparation strategies of MXene-polymer composites including physical mixing, surface modification, such as anchoring through Ti-N and Ti-O-C bonds, bonding through esterification, grafting functional groups through Ti-O-Si/Ti-O-P bonds, photograft reaction, as well as in situ polymerization are highlighted. In addition, the possible mechanisms for each strategy are explained. Furthermore, the applications of MXene-polymer composites obtained by different preparation strategies are summarized. Finally, perspectives and challenges are presented for the designs of MXene-polymer composites.

show abstract

“…This result indicates that the Fe 3+ detection method using the fabricated Ti 3 C 2 MQD-based Fe 3+ biosensor had excellent reproducibility. Another similar example is the development of the fluorescent polylysine-coated Ti 3 C 2 MQD (PL-MQD)-based biosensor for detection of cytochrome c (Cyt c) and trypsin [ 75 ]. Cyt c and trypsin are the important proteins in the cell death process and involve diseases such as pancreatitis, intestinal obstruction, and cystic fibrosis [ 76 , 77 ].…”

Section: Mxene-based Fluorescent/optical Biosensorsmentioning

confidence: 99%

Recent Advances in MXene Nanocomposite-Based Biosensors

et al. 2020

View full text Add to dashboard Cite

The development of advanced biosensors with high sensitivity and selectivity is one of the most demanded concerns in the field of biosensors. To meet this requirement, up until now, numerous nanomaterials have been introduced to develop biosensors for achieving high sensitivity and selectivity. Among the latest nanomaterials attracting attention, MXene is one of the best materials for the development of biosensors because of its various superior properties. MXenes are two-dimensional inorganic compounds with few atomic layers that possess excellent characteristics including high conductivity and superior fluorescent, optical, and plasmonic properties. In this review, advanced biosensors developed on the basis of the MXene nanocomposite are discussed with the selective overview of recently reported studies. For this, introduction of the MXene including the definition, synthesis methods, and its properties are discussed. Next, MXene-based electrochemical biosensors and MXene-based fluorescent/optical biosensors are provided, which are developed on the basis of the exceptional properties of the MXene nanocomposite. This review will suggest the direction for use of the Mxene nanocomposite to develop advanced biosensors with high sensitivity and selectivity.

show abstract

ε-Poly-L-lysine-protected Ti3C2 MXene quantum dots with high quantum yield for fluorometric determination of cytochrome c and trypsin

Cited by 56 publications

References 36 publications

A simple fluorescence assay for trypsin through a protamine-induced carbon quantum dot-quenching aggregation platform

A simple fluorescence assay for trypsin through a protamine-induced carbon quantum dot-quenching aggregation platform

Preparation Strategies and Applications of MXene‐Polymer Composites: A Review

Recent Advances in MXene Nanocomposite-Based Biosensors

Contact Info

Product

Resources

About