γ radiation induced self-assembly of fluorescent molecules into nanofibers: a stimuli-responsive sensing

Han, Ji Min; Wu, Na; Wang, Brian; Wang, Chen; Xu, Miao; Yang, Xiaomei; Yang, Haori

doi:10.1039/c5tc00594a

Cited by 23 publications

(15 citation statements)

References 50 publications

(6 reference statements)

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“…S4b †). Such shiing is likely due to the shielding from the aromatic ring current of the neighbouring coronene and PTCDI core stacking, 30 which is consistent with the p-p stacking arrangement in the single crystal structure. So we attribute the strong D-A p-p stacking (in association with the CT interaction) is the major driving force for the cocrystal growth.…”

supporting

confidence: 59%

Donor–acceptor single cocrystal of coronene and perylene diimide: molecular self-assembly and charge-transfer photoluminescence

Wang

et al. 2017

RSC Adv.

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The research on donor-acceptor (D-A) cocrystalline structures based on organic semiconductive molecules has drawn great attention due to their unique optical and electronic properties. Among the building block molecules, derivatives of perylene-3,4,9,10-tetracarboxylic-3,4,9,10-diimides (PTCDI) are of particular interest as these molecules form high performance n-type semiconductors with strong air stability. However, the cocrystal of PTCDIs remains challenging to fabricate, and only few D-A cocrystals of PTCDIs have been reported. Herein, we report a successful molecular self-assembly design for the PTCDI cocrystal with a donor molecule, coronene. Within the triclinic cell of the cocrystal, the PTCDI and coronene molecules achieved 1 : 1 alternated p-p stacking. The cocrystal showed clear red-shifted absorption and photoluminescence bands, implying the strong charge transfer interaction between coronene and PTCDI. Additionally, the cofacial p-p stacking between coronene and PTCDI planes favors strong one-dimensional self-assembly, leading to the formation of microsized fibril cocrystals and arrays. This presented cocrystal design strategy helps to explore new D-A cocrystalline structures, particularly with one-dimensional morphology control.

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confidence: 59%

Donor–acceptor single cocrystal of coronene and perylene diimide: molecular self-assembly and charge-transfer photoluminescence

Wang

et al. 2017

RSC Adv.

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“…To further determinate the detection limit of current film, we plot a curve of diffuse reflection intensity (at 640 nm) vs. X‐ray dosage (Figure S23) . The curve in the dosage range (0–600 Gy) can be fitted in linear relationship . The detection limit of X‐ray radiation dosage is calculated to be 7.72 Gy.…”

Section: Figurementioning

confidence: 99%

Flexible Viologen‐Based Porous Framework Showing X‐ray Induced Photochromism with Single‐Crystal‐to‐Single‐Crystal Transformation

et al. 2017

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A viologen-based Borromean entangled porous framework was found to be sensitive to both Cu and Mo X-ray sources, showing rapid photochromic response and recovery within one minute. The X-ray-induced photochromic process is accompanied by a reversible single-crystal-to-single-crystal (SC-SC) structural transformation, an unprecedented phenomenon for X-ray sensitive materials. The complex can be further processed into portable thin films for detecting the dose of the X-ray exposure. Moreover, the photochromism can occur over a broad temperature range of 100-333 K, both in the form of single crystals and thin films, making it a potential candidate for practical indoor and outdoor applications.

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“…Furthermore, we infer that ROS cause a disulfide cleavage, which cross-links bAPSC, consequently affecting NP conformation. Han et al recently described markedly sensitive detection of γ-radiation through the fluorescence quenching mechanism by using imidazole-based sensor molecules [ 41 , 42 ].…”

Section: Resultsmentioning

confidence: 99%

Synthesis and Characterization of Dual-Sensitive Fluorescent Nanogels for Enhancing Drug Delivery and Tracking Intracellular Drug Delivery

Debele

Kao

et al. 2017

IJMS

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Here, dual-sensitive fluorescent branched alginate-polyethyleneimine copolymer (bAPSC) nanogels were synthesized from thiolated alginate and stearoyl-derivatized branched polyethyleneimine. The formation of bAPSC conjugates was confirmed through proton nuclear magnetic resonance and Fourier transform infrared spectroscopy, whereas dynamic light scattering was used to measure the particle size and ζ potential of the nanogels. The fluorescent properties of the nanogels were confirmed through fluorescent spectroscopy and microscopy. In addition to the excitation-dependent fluorescence behavior, the fluorescence emission intensity of bAPSC was altered by both pH and γ-irradiation. This intensity was higher at a lower pH than at a higher pH, and it slightly decreased after γ-irradiation. The drug loading and encapsulation efficiency of bAPSC were 25.9% and 11.2%, respectively. An in vitro drug release study revealed that the synthesized nanogels release their doxorubicin (Dox) contents in a time-dependent manner, and the drug release was higher after 96 h of incubation. Approximately 43.74% and 88.36% of Dox was released after 96 h of incubation at pH 5.5 in the absence and presence of glutathione (GSH), respectively. However, relatively lower drug release, approximately 21.6% and 16%, was observed in the presence and absence of GSH at pH 7.4, respectively. Fluorescence microscopy confirmed that Dox-loaded bAPSC nanogels were internalized by HeLa cells, and drug distribution was easily tracked using fluorescent materials without additional probing agents. Moreover, cellular cytotoxicity and hemolysis results revealed less cytotoxicity and hemocompatibility of the synthesized nanogels, confirming that they are the most favorable alternative drug carriers for drug delivery systems.

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γ radiation induced self-assembly of fluorescent molecules into nanofibers: a stimuli-responsive sensing

Abstract: γ radiation causes self-assembly of sensor molecules into a nanofibril structure, enabling stimuli-responsive sensing based on fluorescence and photoconductivity modulation.

Cited by 23 publications

References 50 publications

Donor–acceptor single cocrystal of coronene and perylene diimide: molecular self-assembly and charge-transfer photoluminescence

Donor–acceptor single cocrystal of coronene and perylene diimide: molecular self-assembly and charge-transfer photoluminescence

Flexible Viologen‐Based Porous Framework Showing X‐ray Induced Photochromism with Single‐Crystal‐to‐Single‐Crystal Transformation

Synthesis and Characterization of Dual-Sensitive Fluorescent Nanogels for Enhancing Drug Delivery and Tracking Intracellular Drug Delivery

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