β-Glucan reduces cortisol plasma levels, enhances innate immune system after A. hydrophila inoculation, and has lipolytic effects on the pacu (Piaractus mesopotamicus)

Lopes, Larissa Maria Frazão; Mello, Mariana Maluli Marinho de; Urbinati, Elisabeth Criscuolo

doi:10.1016/j.aquaculture.2021.737411

Cited by 9 publications

(8 citation statements)

References 42 publications

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“…Past studies have shown a similar trend of β-glucan having the ability to lower cortisol in farmed fish species, including striped catfish that was fed with only 4 weeks of β-glucan [52, 53]. It was suggested that the use of β-glucan was suppressing some part of the immune function, though subsequent disease challenges did not find this to be the case [53]. Furthermore, in some species, the use of dietary β-glucan does not have an effect on cortisol levels, e.g., tilapia [54].…”

Section: Discussionmentioning

confidence: 89%

“…The return to prestress levels was only observed in β-glucan dietary groups, while glucose levels also showed a similar trend. Past studies have shown a similar trend of β-glucan having the ability to lower cortisol in farmed fish species, including striped catfish that was fed with only 4 weeks of β-glucan [52,53]. It was suggested that the use of β-glucan was suppressing some part of the immune function, though subsequent disease challenges did not find this to be the case [53].…”

Section: Discussionmentioning

confidence: 95%

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Enhancing farmed striped catfish (Pangasianodon hypophthalmus) robustness using dietary β-glucan

Bano,

Khan,

Fatima

et al. 2023

Preprint

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β-glucan is a well-documented feed additive for its potent immunostimulatory properties in many farmed fish species. This study examined how it can also be a promising growth promoter, modulate antioxidant enzyme activities, and act as an anti-stress agent in striped catfish (Pangasianodon hypophthalmus). A 12-week feeding experiment was untaken to determine the effects of dietary β-glucan supplementation at graded levels (0, 0.5, 1.0, and 1.5 g kg-1). Measured indicators suggest that a dietary inclusion level of 1.5 g kg-1 β-glucan gave the highest positive responses: weight gain (120.10 g fish-1), survival (98.30 %), and lower FCR (1.70) (P<0.05). Whole body proximate analysis had only revealed that crude protein was significantly affected by the dietary inclusion of β-glucan (P<0.05), with the highest protein content (19.70 %) being in fish that were fed with 1.5 g kg-1 β-glucan. Although other inclusion levels (i.e., 0.5 and 1 g kg-1) of β-glucan did not enhance body protein content (P>0.05). The assessment of fatty acid composition in muscle, liver, and adipose tissues showed modifications with the inclusion of β-glucan. Antioxidative-related enzyme activities (inc. catalase, glutathione peroxidase, and superoxide dismutase) that were measured in the liver had higher levels when fed with β-glucan inclusion diets (P<0.05). Following the feed trial, fish were subjected to crowding stress treatment. It was subsequently found that catfish fed with β-glucan-based diet groups had lower levels of blood stress-related indicators compared to the control group with no dietary β-glucan. The use of 1.5 g kg-1 of dietary β-glucan resulted in the lowest measured levels of cortisol (43.13 ng mL-1) and glucose (50.16 mg dL-1). This study has demonstrated that the dietary inclusion of β-glucan can have functional benefits beyond the immunological enhancements in striped catfish. Furthermore, its use can increase production levels and mitigate the stress associated with intensive farming practices.

show abstract

Section: Discussionmentioning

confidence: 89%

Section: Discussionmentioning

confidence: 95%

Enhancing farmed striped catfish (Pangasianodon hypophthalmus) robustness using dietary β-glucan

Bano,

Khan,

Fatima

et al. 2023

Preprint

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“…Viral diseases affect bony fish that can occur immediately and cause overwhelming deaths in the majority of farmed fish ( 23 ). The defense responses through the use of immunostimulants could be efficient to suppress the viral infection in fish to an extent ( 29 , 30 ). Numerous studies reported that β-glucan could enhance the resistance to bacterial infection in fish like Yersinia ruckeri , Flavobacterium columnare , Aeromonas salmonicida , and A. hydrophila ( 29 , 31 , 32 ).…”

Section: Discussionmentioning

confidence: 99%

“…The defense responses through the use of immunostimulants could be efficient to suppress the viral infection in fish to an extent ( 29 , 30 ). Numerous studies reported that β-glucan could enhance the resistance to bacterial infection in fish like Yersinia ruckeri , Flavobacterium columnare , Aeromonas salmonicida , and A. hydrophila ( 29 , 31 , 32 ). Its resistance to viral diseases has also been reported such as grass carp hemorrhage virus, viral hemorrhagic septicemia virus, and nervous necrosis virus ( 33 ; 30 , 34 ).…”

Section: Discussionmentioning

confidence: 99%

Supplementation of Dietary Crude Lentinan Improves the Intestinal Microbiota and Immune Barrier in Rainbow Trout (Oncorhynchus mykiss) Infected by Infectious Hematopoietic Necrosis Virus

Ren

Zhao

et al. 2022

Front. Immunol.

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The effects of crude lentinan (CLNT) on the intestinal microbiota and the immune barrier were evaluated in rainbow trout (Oncorhynchus mykiss) infected by infectious hematopoietic necrosis virus (IHNV). The results showed that supplementary CLNT declined the rainbow trout mortality caused by IHNV, which suggested that CLNT has preventive effects on IHNV infection. IHNV destroyed intestinal integrity, as well as caused the intestinal oxidative and damage in rainbow trout. Supplementary CLNT significantly strengthened the intestinal immune barrier by declining intestinal permeability, as well as enhancing intestinal antioxidant and anti-inflammatory abilities in IHNV-infected rainbow trout (P<0.05). In addition, CLNT modified the aberrant changes of intestinal microbiota induced by IHNV, mainly represented by promoting the growths of Carnobacterium and Deefgea and inhibiting Mycobacterium and Nannocystis. Especially, supplementing with CLNT significantly promoted the growth of short-chain fatty acid–producing bacteria (P<0.05) and consequently increased the production of acetic acid, butanoic acid, and hexanoic acid in the intestine of IHNV-infected rainbow trout. Furthermore, it was speculated that CLNT could regulate the self-serving metabolic pathways of intestinal microbiota induced by IHNV, such as fatty acid metabolism and amino acid metabolism. Together, CLNT played the antiviral effects on IHNV infection through strengthening the intestinal immune barrier, as well as regulating intestinal microbiota and SCFA metabolism in rainbow trout. The present data revealed that CLNT exerted a promising prebiotic role in preventing the rainbow trout from IHNV infection.

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“…The return to prestress levels was only observed in β-glucan dietary groups, while glucose levels also showed a similar trend. Past studies have shown a similar trend of βglucan having the ability to lower cortisol in farmed fish species, including striped catfish that was fed with only 4 weeks of β-glucan [17,57]. It was suggested that the use of β-glucan was suppressing some part of the immune function, though subsequent disease challenges did not find this to be the case [57].…”

Section: Plos Onementioning

confidence: 95%

Enhancing farmed striped catfish (Pangasianodon hypophthalmus) robustness through dietary β-glucan

Bano,

Khan,

Fatima

et al. 2024

PLoS ONE

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β-glucan is a well-documented feed additive for its potent immunostimulatory properties in many farmed fish species. This study examined how it can also be a promising growth promoter, modulate antioxidant enzyme activities, and act as an anti-stress agent in striped catfish (Pangasianodon hypophthalmus). A 12-week feeding experiment was untaken to determine the effects of dietary β-glucan supplementation at graded levels (0, 0.5, 1.0, and 1.5 g kg-1). Measured indicators suggest that a dietary inclusion level of 1.5 g kg-1 β-glucan gave the highest positive responses: weight gain (120.10 g fish-1), survival (98.30%), and lower FCR (1.70) (P<0.05). Whole body proximate analysis had only revealed that crude protein was significantly affected by the dietary inclusion of β-glucan (P<0.05), with the highest protein content (19.70%) being in fish that were fed with 1.5 g kg-1 β-glucan. Although other inclusion levels (i.e., 0.5 and 1 g kg-1) of β-glucan did not enhance body protein content (P>0.05). The assessment of fatty acid composition in muscle, liver, and adipose tissues showed modifications with the inclusion of β-glucan. Antioxidative-related enzyme activities (inc. catalase, glutathione peroxidase, and superoxide dismutase) that were measured in the liver had higher levels when fed with β-glucan inclusion diets (P<0.05). Following the feed trial, fish were subjected to crowding stress treatment. It was subsequently found that catfish fed with β-glucan-based diet groups had lower levels of blood stress-related indicators compared to the control group with no dietary β-glucan. The use of 1.5 g kg-1 of dietary β-glucan resulted in the lowest measured levels of cortisol (43.13 ng mL-1) and glucose (50.16 mg dL-1). This study has demonstrated that the dietary inclusion of β-glucan can have functional benefits beyond the immunological enhancements in striped catfish. Furthermore, its use can increase production levels and mitigate the stress associated with intensive farming practices.

show abstract

β-Glucan reduces cortisol plasma levels, enhances innate immune system after A. hydrophila inoculation, and has lipolytic effects on the pacu (Piaractus mesopotamicus)

Cited by 9 publications

References 42 publications

Enhancing farmed striped catfish (Pangasianodon hypophthalmus) robustness using dietary β-glucan

Enhancing farmed striped catfish (Pangasianodon hypophthalmus) robustness using dietary β-glucan

Supplementation of Dietary Crude Lentinan Improves the Intestinal Microbiota and Immune Barrier in Rainbow Trout (Oncorhynchus mykiss) Infected by Infectious Hematopoietic Necrosis Virus

Enhancing farmed striped catfish (Pangasianodon hypophthalmus) robustness through dietary β-glucan

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