β-Glucan augments IL-1β production by activating the JAK2/STAT3 pathway in cultured rabbit keratinocytes

Xiao, Wudian; Fu, Lu; Gu, Chunping; Wang, Ran; Zhao, Mingde; Wang, Jie; Jia, Xianbo; Chen, Shiyi; Lai, Songjia

doi:10.1016/j.micpath.2020.104175

Cited by 2 publications

(1 citation statement)

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“…It is a polysaccharide that has several benefits. It aids in digestion and has anti‐diabetic, antioxidant, heart protecting and antimicrobial capabilities (Sun et al., 2020; Xiao et al., 2020).…”

Section: Introductionmentioning

confidence: 99%

Compounds extracted from solid fermentation of Pleurotus sajor‐caju for application as a natural antibacterial agent

Contessa

Souza

Almeida

et al. 2021

Food Processing Preservation

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Edible mushrooms have been the object of studies regarding their bioactive properties, acting mainly in the pharmaceutical and food areas. This study aimed at the production, extraction and purification of antibacterial compounds from Pleurotus sajor‐caju. The identification of these compounds occurred by analysis via FT‐Raman spectroscopy. Antibacterial extraction had a positive response, resulting in two compounds. The compound extracted at 25°C inhibited the development of Staphylococcus aureus by 52.7 ± 2.7 (%). The compound had a molecular size greater than 100 kDa and a possibly little branched structure. At a temperature of 60°C, the compound with the greatest antagonistic activity against Escherichia coli, reduced its development by 74.3 ± 1.8 (%). The compound was possibly a linear or slightly branched chain biomolecule and molecular weight between 50 and 100 kDa. According to the literature, it is estimated that the extracted compounds refer to β‐glucan structures. Novelty impact statement The extract showed potential of inhibition above 50% for gram‐positive and gram‐negative microorganisms. The purification processes were efficient, reaching a 23.5‐fold increase in bioactive capacity. It is estimated that different β‐glucan structures were extracted.

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Section: Introductionmentioning

confidence: 99%