β-D-glucan from marine yeast Debaryomyces hansenii BCS004 enhanced intestinal health and glucan-expressed receptor genes in Pacific red snapper Lutjanus peru

Reyes‐Becerril, Martha; Angulo, Miriam; Sánchez, Verónica; Guluarte, Crystal; Angulo, Carlos

doi:10.1016/j.micpath.2020.104141

Cited by 16 publications

(16 citation statements)

References 39 publications

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“…Probiotics are rich in β‐glucan, and this compound enhances the immune response (Gatesoupe, 2007; Giri et al, 2015). Recently, Reyes‐Becerril et al (2020) observed that DhBCS004—rich in β‐D‐glucan—could up‐regulate macrophage receptor genes in the gut of L. peru .…”

Section: Discussionmentioning

confidence: 99%

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Probiotic properties of Debaryomyces hansenii BCS004 and their immunostimulatory effect in supplemented diets for gilthead seabream ( Sparus aurata )

Reyes‐Becerril

Angulo

et al. 2021

Aquaculture Research

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Debaryomyces hansenii BCS004 strain is a non‐pathogenic, polyamine and superoxide dismutase secreting marine yeast. The objective of this study was to investigate the marine yeast DhBCS004 as probiotics and evaluate its antimicrobial properties and dietary immunostimulant effect on gilthead seabream specimens when administered at 106 colony‐forming unit/g−1 or 1.1% for 4 weeks. This yeast strain showed potential probiotic properties, including stability in gastrointestinal survival (pH, bile conditions) and attachment to intestinal cells. The DhBCS004 had antimicrobial activity against important marine pathogens. Interestingly, this yeast has a high amount of n−3 polyunsaturated fatty acids with high concentrations of oleic and linoleic acids, which may confer nutritional and therapeutic values. The in vivo immunological assay revealed that dietary DhBCS004 significantly increased phagocytosis capacity, peroxidase and respiratory burst activities in leucocytes. Furthermore, the natural haemolytic complement activity and total IgM levels increased in serum after weeks 2 or 4 of trial. Finally, DhBCS004 significantly increased the transcriptions of TNF‐α, C3 and IgM in intestine samples. This work reinforces the biotechnological and immunological potential of D. hansenii BCS004 in the field of fish aquaculture.

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Section: Discussionmentioning

confidence: 99%

“…Recently, Reyes-Becerril et al (2020) observed that DhBCS004rich in β-D-glucan-could up-regulate macrophage receptor genes in the gut of L. peru.…”

Section: Discussionmentioning

confidence: 99%

Probiotic properties of Debaryomyces hansenii BCS004 and their immunostimulatory effect in supplemented diets for gilthead seabream ( Sparus aurata )

Reyes‐Becerril

Angulo

et al. 2021

Aquaculture Research

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“…Up to now, the main yeast strains for β-glucan extraction have been those belonging to Saccharomyces cerevisiae . However, non- Saccharomyces cerevisiae strains have also been tested with promising results, such as Saccharomyces uvarum [ 31 ], Yarrowia lipolytica N6 [ 61 ], Sterigmatomyces halophilus [ 18 ], Debaryomyces hansenii BCS004 [ 26 ], and Cystobasidium benthicum [ 22 ]. Remarkably, many studies have related β-glucan supplementation to increased disease resistance in fish.…”

Section: Effects Of Yeast β-Glucans On Fish Immune Systemmentioning

confidence: 99%

“…For instance, β-glucan from the marine yeast Debaryomyces hansenii BCS004 in Pacific snapper ( Lutjanus peru ) generated a cell proliferation effect, its inclusion in the diet (500 mg/kg) did not cause histopathological damage to the intestine, and it positively upregulated macrophage receptor genes. It also showed antioxidant properties that could help to reduce oxidative stress caused by ROS and RNS generated by different pathogens [ 26 ]. On the other hand, also in Pacific snapper, a dose of 200 μg/kg of β-glucan isolated from an extreme marine environment yeast ( Sterigmatomyces halophilus ) induced activity in vitro in different processes within phagocytic cells, and increased the transcription levels of anti- and pro-inflammatory genes.…”

Section: Effects Of Yeast β-Glucans On Fish Immune Systemmentioning

confidence: 99%

“…The difference in immunostimulatory capacity could also be attributed to structure and molecular weight. For instance, β-glucan from Debaryomyces hansenii BCS004 measures 689.35 kDa [ 26 ] compared to 175 kDa (bakery) [ 23 ] and 240 kDa (brewery) for S. cerevisiae [ 25 ]. However, this is an unresolved hypothesis, as there are β-glucans with low molecular weight such as the kind extracted from the yeast Cystobasidium benthicum (2.32 kDa) that have proved to be a potential immunostimulant [ 22 ].…”

Section: Perspectivesmentioning

confidence: 99%

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Yeast β-Glucans as Fish Immunomodulators: A Review

Machuca

Méndez-Martínez

Reyes‐Becerril

et al. 2022

Animals

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Administration of immunostimulants in fish is a preventive method to combat infections. A wide variety of these biological molecules exist, among which one of the yeast wall compounds stands out for its different biological activities. The β-glucan that forms the structural part of yeast is capable of generating immune activity in fish by cell receptor recognition. The most frequently used β-glucans for the study of mechanisms of action are those of commercial origin, with doses recommended by the manufacturer. Nevertheless, their immune activity is inefficient in some fish species, and increasing the dose may show adverse effects, including immunosuppression. Conversely, experimental β-glucans from other yeast species show different activities, such as antibacterial, antioxidant, healing, and stress tolerance properties. Therefore, this review analyses the most recent scientific reports on the use of yeast β-glucans in freshwater and marine fish.

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Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2019–2020

Harvey

2023

Mass Spectrometry Reviews

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This review is the tenth update of the original article published in 1999 on the application of matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry to the analysis of carbohydrates and glycoconjugates and brings coverage of the literature to the end of 2020. Also included are papers that describe methods appropriate to analysis by MALDI, such as sample preparation techniques, even though the ionization method is not MALDI. The review is basically divided into three sections: (1) general aspects such as theory of the MALDI process, matrices, derivatization, MALDI imaging, fragmentation, quantification and the use of arrays. (2) Applications to various structural types such as oligo‐ and polysaccharides, glycoproteins, glycolipids, glycosides and biopharmaceuticals, and (3) other areas such as medicine, industrial processes and glycan synthesis where MALDI is extensively used. Much of the material relating to applications is presented in tabular form. The reported work shows increasing use of incorporation of new techniques such as ion mobility and the enormous impact that MALDI imaging is having. MALDI, although invented nearly 40 years ago is still an ideal technique for carbohydrate analysis and advancements in the technique and range of applications show little sign of diminishing.

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β-D-glucan from marine yeast Debaryomyces hansenii BCS004 enhanced intestinal health and glucan-expressed receptor genes in Pacific red snapper Lutjanus peru

Cited by 16 publications

References 39 publications

Probiotic properties of Debaryomyces hansenii BCS004 and their immunostimulatory effect in supplemented diets for gilthead seabream ( Sparus aurata )

Probiotic properties of Debaryomyces hansenii BCS004 and their immunostimulatory effect in supplemented diets for gilthead seabream ( Sparus aurata )

Yeast β-Glucans as Fish Immunomodulators: A Review

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2019–2020

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