β‐Cyclodextrin PAMAM Dendrimer Surface Doped with Silver and Hexacyanoferrate (III) and its Applications for Dopamine Detection in Synthetic Samples

Abstract

A synthesis of β-cyclodextrin (β-Cd) functionalized with polyamide dendrimer PAMAM G.0 complexed with silver and potassium hexacyanoferrate (III) forming a mixed-valence complex (β-Cd-PAMAM-Ag/Fe) was proposed. This material was characterized by scanning electron microscopy (SEM), infrared spectroscopy (FT-IR), X-Ray diffraction (XRD), Energy Dispersion Spectroscopy (EDS) and Electron Paramagnetic Resonance (EPR). The hybrid complex was electrochemically investigated using cyclic voltammetry and some parameters (electrolyte, concentration of electrolyte, pH and scan rate) were evaluate in order to obtain optimum analytical responses. The β-Cd-PAMAM-Ag/Fe material was successfully applied in the electrocatalytic oxidation of dopamine (DOP) using Cyclic Voltammetry (CV) and Square Wave Voltammetry (SWV).

Integration of Hybrid Dendrimers and Their Generations for Modulated Spatio‐Temporal Action

“…Cyclodextrin is a macrocyclic receptor with hydrophobic cavity and forms a supramolecular inclusion complex along with PAMAM dendrimers G0 (named Tetra-CD) using copper(I)-catalyzed alkyne-azide cycloaddition (CuAAC) presents a considerably high-water solubility (>2580 mg mL −1 ) compared to native system (18.3 mg mL −1 ). [78] β-cyclodextrin grafted PAMAM dendrimers G0 with silver and potassium hexacyanoferrate(III) develop a mixed valency complex to determine the dopamine in synthetic samples by electrolytic oxidation of dopamine. [79] Nanocapsules of biocompatible shells prepared with β-cyclodextrin (β-CD)-modified dendrimers G1 and G2 activated with acidic groups, possesses high drug loading capacity for encapsulation, stability, and used for sustained delivery of naltrexone (NLX).…”

“…Cyclodextrin is a macrocyclic receptor with hydrophobic cavity and forms a supramolecular inclusion complex along with PAMAM dendrimers G0 (named Tetra‐CD) using copper(I)‐catalyzed alkyne‐azide cycloaddition (CuAAC) presents a considerably high‐water solubility (>2580 mg mL −1 ) compared to native system (18.3 mg mL −1 ). [ 78 ] β‐cyclodextrin grafted PAMAM dendrimers G0 with silver and potassium hexacyanoferrate(III) develop a mixed valency complex to determine the dopamine in synthetic samples by electrolytic oxidation of dopamine. [ 79 ]…”