β-Cyclodextrin grafted gold nanoparticles with short molecular spacers applied for nanosensors based on plasmonic effects

UV–vis Study on β‐Cyclodextrin as Dual Function for Synthesis AgNPs and Antibacterial Application

“…The stability of AgNPs was caused by the ability of β‐CDs to form an inclusion complex with another molecule and protect it from light, heat, oxygen, and chemical reactions. [ 8,10 ] There was a slight increase in the absorbance intensity over 4 weeks, which was 0.0444 (5.1%). This phenomenon was caused by the ongoing reduction of Ag + to Ag 0 during the storage time.…”

“…[7] Cyclodextrins (CDs) are non-toxic cyclic oligosaccharides containing 6, 7, or 8 units of D-glucose (named as 𝛼-, 𝛽-, and 𝛾-CDs, respectively) linked by 𝛼-1,4 glycosidic bond. [8] 𝛼, 𝛽, and 𝛾-CDs have inner diameters of 4.5, 7.8, and 9.2 Å, respectively. 𝛽-CDs are toroidal in shape with some physicochemical properties, such as water-solubility, hydrophilic exterior and hydrophobic cavity, and high molecular weight.…”

Development of nano- and microdevices for the next generation of biotechnology, wearables and miniaturized instrumentation

“…For example, the use of synthetic molecular receptors such as cyclodextrins attached to gold nanoparticles allowed improved laser dyes detection based on enhanced plasmonic effects. 95 This research work showed how modifications to the medium could control from single grafted nanoparticle detection to higher-sized nanoaggregates, with potential uses for photonic surface applications. But the importance of the potential use of single nanoplatforms to design lab-on-particles should be highlighted as well, where biodetection and targeted application of treatments could be combined if required by smart responsive stimulus.…”

“…However, signal transduction from single nanoparticles by arrival of individual targeted molecules on these smart responsive optical nanoplatforms could be limited depending on the detection strategy. But promising results from highly sensitive approaches have led to detection in very low molecular concentrations within nM and femto-M. 87,95 The values achieved were also recorded with advanced microscopy setups and with microuidic systems coupled with imaging detections systems. However, for implantable and wearables such optics levels could constrain portable applications; but this apparent hindrance could be overcome by adding time to collect a higher number of targeted molecules on particles to enhance detection, e.g.…”

Synthetic non-classical luminescence generation by enhanced silica nanophotonics based on nano-bio-FRET

“…28 Thus, the higher frequency of dimeric forms of the silica nanoparticles obtained by us was explained as due to an optimal ratio of available surface and forces for intermediate particle sizes of 200-300 nm, and not just obtained by Brownian motion and encountering. This fact prompted our interest to study potential applications of dimeric forms by chemical modication of the nano-surfaces with short molecular spacers [29][30][31] for non-classical light generation 32 and nano-resolution. 33 In addition, the enhanced surfaces accompanied by higher emission properties from SiO 2 -RhB-Fl nanoparticles were explained by FRET.…”