β-CD-SO3H: Synthesis, Characterization and Its Application for the Synthesis of Benzylpyrazolyl Naphthoquinone and Pyrazolo Pyranopyrimidine Derivatives in Water

Recent Advances in the Synthesis of 2-Hydroxy-1,4-naphthoquinone (Lawsone) Derivatives

“…To synthesize Dihydro-1H-pyrazolyl Naphthalene-1,4-dione derivatives 115a-s, a mixture containing 3-methyl-1-phenyl-1Hpyrazol-5-ol 114(1 mmol), substituted aldehyde 113a-s(1 mmol), and 2-hydroxy naphthoquinone 1 (1 mmol) in 5 mL of water, along with 10 mol% β-CD-SO3H catalyst, was stirred at room temperature (Scheme 36). 66 Scheme 36 Synthesis of dihydro-1H-pyrazolyl Naphthalene-1,4-dione derivatives 115a-s.…”

“…Patil et al 66 presented a green and cost-effective method for synthesizing benzylpyrazolyl naphthoquinone in water at room temperature, utilizing β-CD-SO 3 H as a catalyst. This protocol demonstrates environmental friendliness by employing a heterogeneous and reusable catalyst in a green reaction medium.…”

“…64 These derivatives have demonstrated diverse biological activities such as antibacterial, anti-HIV, antiviral, anticoagulant, antioxidant, and anticancer properties. 65 Patil et al 66 presented a green and cost-effective method for synthesizing benzylpyrazolyl naphthoquinone in water at room temperature, utilizing -CD-SO 3 H as a catalyst. This protocol demonstrates environmental friendliness by employing a heterogeneous and reusable catalyst in a green reaction medium.…”

Synthesis of benzoin under supramolecular catalysis involving cyclodextrins in water: application for the preparation of the antiepileptic drug phenytoin

“…4 Due to their remarkable inclusion capabilities with small organic molecules, more recent interests focus on organic reactions catalyzed by CDs and their modified derivatives. 5–8…”

“…4 Due to their remarkable inclusion capabilities with small organic molecules, more recent interests focus on organic reactions catalyzed by CDs and their modied derivatives. [5][6][7][8] Benzoin, 2-hydroxy-1,2-diphenylethanone, is an important chemical intermediate, and has been widely used as a photosensitizer for photosensitive resins, gravure inks, and photocurable coatings as well as a catalyst for the production of polyesters. [9][10][11] The old-fashioned method for synthesizing benzoin is catalyzed by cyanide, which consisted of toxic substances and caused environmental pollution.…”