Abstract:Introduction. β-Caryophyllene (BCP) has been shown to be an effective
anti-inflammatory agent in chronic and inflammatory pain models. Since
limited data are available for BCP in acute pain, we tested efficacy of
BCP in an acute post-surgical pain model. Methods. BCP was tested in an
acute postsurgical pain model. Animals were treated with vehicle, 10,
25, 50 and 75 mg/kg BCP that was injected intra-peritoneally (i.p.).
Time dependent paw withdrawal response (PWR) were evaluated using von
Frey filaments and pl… Show more
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