β-carotene and α-tocopherol coencapsulated in nanostructured lipid carriers of murumuru (<i>Astrocaryum murumuru</i>) butter produced by phase inversion temperature method: characterisation, dynamic<i>in vitro</i>digestion and cell viability study

Gomes, Graziela V. L.; Sola, Mirella R.; Rochetti, Arina Lázaro; Fukumasu, Heidge; Vicente, António A.; Pinho, Samantha C.

doi:10.1080/02652048.2019.1585982

Cited by 29 publications

(21 citation statements)

References 44 publications

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“…Pereira et al (2019) found similar results to those obtained in the present study for the composition of murumuru butter. Due to its chemical composition, being rich in unsaturated fatty acid, this butter showed potential properties for the development of nanoparticles (Gomes et al, 2019) and biocosmetics (Silva et al, 2014). Bacuri butter presented palmitic and oleic acids as its major fatty acids, corroborating with the results of the supplier report.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of the quality of Amazonian butters as sustainable raw materials for applications in bioproducts

Feitosa

Silva

Fonseca

et al. 2021

Rev. Ciênc. Farm. Básica Apl.

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A new consumer profile for pharmaceutical and cosmetic products has motivated research into natural raw materials in the development of "green" products such as herbal medicines and biocosmetics. However, various limitations have been encountered in the marketing of these products, for example the quality control of the natural raw materials used by the industrial market. This study aims to evaluate the sensory and physicochemical parameters of murumuru (Astrocaryum murumuru Mart.), bacuri (Platonia insignis Mart.), tucuma (Astrocaryum vulgare Mart.), and ucuuba (Virola sebifera Aubl.) butters for applications in pharmaceutical and cosmetic bioproducts. The acidity and saponification as well as the iodine and peroxide indexes were evaluated and fatty acid profiles for the samples obtained by GC-MS. The sensory properties of the butters showed the appearance of solid to soft cream, color (yellow, brown, buttercup, and ochre), and characteristic odor. The melting temperatures of all butters ranged between 31 ºC and 49 °C. The acidity, saponification, iodine and peroxide indexes for the butters were of 5.82-17.73 mg (NaOH or KOH) g −1 , 181.10-573.55 mg KOH g −1 , 2.78-44.96 gl 2 100 g −1 , and 1.39-9.30 meq kg −1 , respectively. From analyses of the fatty acid profiles, the major components identified were lauric acid in murumuru (40%) and ucuuba butters (73%), myristic acid in tucuma butter (53%), and palmitic acid in bacuri butter (42%). In general, the results of the analyses differed from the specifications of the supplier reports and official compendia. These findings highlight the importance of quality control in natural raw materials to ensure their functionality in pharmaceutical and cosmetic bioproducts.

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Section: Discussionmentioning

confidence: 99%

Evaluation of the quality of Amazonian butters as sustainable raw materials for applications in bioproducts

Feitosa

Silva

Fonseca

et al. 2021

Rev. Ciênc. Farm. Básica Apl.

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“…SLNs and NLCs prepared using this method have been reported to have small PSs, narrow size distribution, and excellent stabilities [ 118 , 119 ]. For example, NLCs loaded with β-carotene and α-tocopherol had a PS of 35 nm [ 120 ]. This method requires little energy input and does not require organic solvents.…”

Section: Methods For Slns and Nlcs Preparationmentioning

confidence: 99%

Preparation of Solid Lipid Nanoparticles and Nanostructured Lipid Carriers for Drug Delivery and the Effects of Preparation Parameters of Solvent Injection Method

2020

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Solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) have emerged as potential drug delivery systems for various applications that are produced from physiological, biodegradable, and biocompatible lipids. The methods used to produce SLNs and NLCs have been well investigated and reviewed, but solvent injection method provides an alternative means of preparing these drug carriers. The advantages of solvent injection method include a fast production process, easiness of handling, and applicability in many laboratories without requirement of complicated instruments. The effects of formulations and process parameters of this method on the characteristics of the produced SLNs and NLCs have been investigated in several studies. This review describes the methods currently used to prepare SLNs and NLCs with focus on solvent injection method. We summarize recent development in SLNs and NLCs production using this technique. In addition, the effects of solvent injection process parameters on SLNs and NLCs characteristics are discussed.

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“…Current literature reports use various fabrication methods for NLCs including, highpressure homogenization at high or low temperatures (including cold homogenization and hot homogenization) [335], solvent emulsification-diffusion techniques [331], supercritical fluids (supercritical fluid extraction of emulsion) [336], solvent emulsification evaporation [335], solvent displacement [135], solvent diffusion [337], phase inversion [338,339], melt emulsification [340], sonication [334], spray-drying [340,341], and solvent evaporation [335].…”

Section: Nanostructured Lipid Carriers (Nlcs)mentioning

confidence: 99%

Fate of β-Carotene within Loaded Delivery Systems in Food: State of Knowledge

et al. 2021

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Nanotechnology has opened new opportunities for delivering bioactive agents. Their physiochemical characteristics, i.e., small size, high surface area, unique composition, biocompatibility and biodegradability, make these nanomaterials an attractive tool for β-carotene delivery. Delivering β-carotene through nanoparticles does not only improve its bioavailability/bioaccumulation in target tissues, but also lessens its sensitivity against environmental factors during processing. Regardless of these benefits, nanocarriers have some limitations, such as variations in sensory quality, modification of the food matrix, increasing costs, as well as limited consumer acceptance and regulatory challenges. This research area has rapidly evolved, with a plethora of innovative nanoengineered materials now being in use, including micelles, nano/microemulsions, liposomes, niosomes, solidlipid nanoparticles, nanostructured lipids and nanostructured carriers. These nanodelivery systems make conventional delivery systems appear archaic and promise better solubilization, protection during processing, improved shelf-life, higher bioavailability as well as controlled and targeted release. This review provides information on the state of knowledge on β-carotene nanodelivery systems adopted for developing functional foods, depicting their classifications, compositions, preparation methods, challenges, release and absorption of β-carotene in the gastrointestinal tract (GIT) and possible risks and future prospects.

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β-carotene and α-tocopherol coencapsulated in nanostructured lipid carriers of murumuru (Astrocaryum murumuru) butter produced by phase inversion temperature method: characterisation, dynamicin vitrodigestion and cell viability study

Cited by 29 publications

References 44 publications

Evaluation of the quality of Amazonian butters as sustainable raw materials for applications in bioproducts

Evaluation of the quality of Amazonian butters as sustainable raw materials for applications in bioproducts

Preparation of Solid Lipid Nanoparticles and Nanostructured Lipid Carriers for Drug Delivery and the Effects of Preparation Parameters of Solvent Injection Method

Fate of β-Carotene within Loaded Delivery Systems in Food: State of Knowledge

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