2008
DOI: 10.1016/j.foodchem.2007.07.064
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α-Glucosidase inhibitory effect by the flower buds of Tussilago farfara L.

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Cited by 117 publications
(84 citation statements)
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“…Chebulagic acid was a reversible and noncompetitive inhibitor of intestinal maltase and a more potent inhibitor of maltase-glucoamylase complex than that of sucrase-isomaltase complex 28 . Compounds like 3,4-dicaffeoylquinic acid, 3,5-dicaffeoylquinic acid and 4,5-dicaffeoylquinic acid isolated from the flower buds of Tussilago farfara L. also inhibited intestinal maltase activity but with IC 50 value in mM range 29 . The Dixon plots and S/v vs I plots showed that nimbidiol inhibited various glucosidases in a mixed competitive fashion (Figures 2-5).…”
Section: Discussionmentioning
confidence: 99%
“…Chebulagic acid was a reversible and noncompetitive inhibitor of intestinal maltase and a more potent inhibitor of maltase-glucoamylase complex than that of sucrase-isomaltase complex 28 . Compounds like 3,4-dicaffeoylquinic acid, 3,5-dicaffeoylquinic acid and 4,5-dicaffeoylquinic acid isolated from the flower buds of Tussilago farfara L. also inhibited intestinal maltase activity but with IC 50 value in mM range 29 . The Dixon plots and S/v vs I plots showed that nimbidiol inhibited various glucosidases in a mixed competitive fashion (Figures 2-5).…”
Section: Discussionmentioning
confidence: 99%
“…These samples represented natural populations of coltsfoot from different regions of Poland ( Fig. 1): Western Pomerania (localities 1-2), the Lubusz region (3), Greater Poland (4)(5)(6)(7)(8)(9)(10)(11)(12), Upper Silesia and Dąbrowa Basin (13)(14)(15), Lesser Poland (16)(17)(18), and the Cieszyn Silesia (19)(20). The investigated populations of T. farfara occurred in different types of habitats, mainly anthropogenic ones such as roadsides and roadside ditches as well as fallow lands.…”
mentioning
confidence: 99%
“…asthma), acting as a weak platelet activating factor antagonist and a Ca 2+ channel blocker [17]. The extracts of Farfarae flos exhibit various activities, such as antioxidant [18,19], antiinflammatory [20] and antimicrobial [21][22][23]; what is more, they also inhibit some enzymes including α-glucosidase [24], NO synthetase in the LPS-activated macrophages or murine microglial cells [8,25] and diacylglycerol acyltransferase [26].…”
mentioning
confidence: 99%