α-Glucosidase inhibitory, antibacterial, and antioxidant activities of natural substances from the wood of <i>Derris reticulata</i> Craib

Issarachot, Papawarin; Sangkaew, Warissara; Sianglum, Wipawadee; Saeloh, Dennapa; Limsuwan, Surasak; Voravuthikunchai, Supayang Piyawan; Joycharat, Nantiya

doi:10.1080/14786419.2019.1678610

Cited by 9 publications

(4 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Derris reticulata Craib, a climbing medicinal plant used in folk medicine [154], has prenylated flavanones as its main constituents, whose presence has been linked to several pharmacological outcomes, particularly antibacterial activity [154,155]. According to Pulbutr et al [155], the ethanolic extract from stems of D. reticulata was able to inhibit S. mutans DMST 1877 biofilm formation by up to 99.9%, at the highest tested concentration, 750 µg•µL −1 .…”

Section: The Most Promising Medicinal Plant Extracts In the Control Of Oral Biofilmsmentioning

confidence: 99%

Antimicrobials from Medicinal Plants: An Emergent Strategy to Control Oral Biofilms

et al. 2021

View full text Add to dashboard Cite

Oral microbial biofilms, directly related to oral diseases, particularly caries and periodontitis, exhibit virulence factors that include acidification of the oral microenvironment and the formation of biofilm enriched with exopolysaccharides, characteristics and common mechanisms that, ultimately, justify the increase in antibiotics resistance. In this line, the search for natural products, mainly obtained through plants, and derived compounds with bioactive potential, endorse unique biological properties in the prevention of colonization, adhesion, and growth of oral bacteria. The present review aims to provide a critical and comprehensive view of the in vitro antibiofilm activity of various medicinal plants, revealing numerous species with antimicrobial properties, among which, twenty-four with biofilm inhibition/reduction percentages greater than 95%. In particular, the essential oils of Cymbopogon citratus (DC.) Stapf and Lippia alba (Mill.) seem to be the most promising in fighting microbial biofilm in Streptococcus mutans, given their high capacity to reduce biofilm at low concentrations.

show abstract

Section: The Most Promising Medicinal Plant Extracts In the Control Of Oral Biofilmsmentioning

confidence: 99%

Antimicrobials from Medicinal Plants: An Emergent Strategy to Control Oral Biofilms

et al. 2021

View full text Add to dashboard Cite

show abstract

“…D. reticulata has also been shown to exhibit antioxidant activity. 11,16 It is widely known that inflammatory processes cause an increase in the formation of free radicals. [4][5][6][7] In addition, it has been reported that D. reticulata extract significantly reduces NO production and the expression of several mRNAs and proteins which are proinflammatory cytokines, TNF-α, IL-1 and IL-6, and the enzymes, iNOS and COX-2.…”

Section: In Vivo Anti-inflammatory Activity Of Drementioning

confidence: 99%

“…[11][12] Previous studies have shown that this plant also exerts estrogenic, 13 anticariogenic, 14 antibacterial, antiviral, anti-cancer, -glucosidase inhibitory, antidiabetic, and antioxidant activities. 11,[15][16] Moreover, it has also been shown that ethanol extract from the stem of D. reticulata significantly reduces nitric oxide (NO) production and the mRNA expression of pro-inflammatory cytokines of macrophages, which reveals its anti-inflammatory effect. 17 To the best of our knowledge, no previous pharmacological study has investigated the anti-inflammatory potential of D. reticulata in an animal model.…”

Section: Introductionmentioning

confidence: 99%

In vivo Anti-Inflammatory Activity of Derris reticulata Ethanol Extract

2021

TJNPR

View full text Add to dashboard Cite

Derris reticulata Craib. has been used in Thai traditional medicine to treat various inflammatory diseases. Recently, D. reticulata extract has been reported to exert anti-inflammatory activity by inhibiting nitric oxide (NO) secretion and the expression of various mRNAs in stimulated macrophage cells. However, studies of its anti-inflammatory effects in an animal model have not been performed. The study evaluated the in vivo anti-inflammatory activity of an ethanol extract of the wood of D. reticulata (DRE). The anti-inflammatory effect of DRE on ethyl phenylpropiolate (EPP)-induced ear edema and carrageenan-induced paw edema in rats was studied. Furthermore, the NO scavenging activity and phytochemical contents of the DRE were determined. The results showed that the most abundant phytochemical compound was lupinifolin, followed by total proanthocyanidin, total phenolic compounds, and total flavonoids. DRE also exhibited NO scavenging activity (15.8 -49.7%) while 1%, 5%, and 10% DRE promoted a significant reduction of inflammation in EPP-induced rat ear edema (35.0 -52.5%) and carrageenan-induced rat paw edema (28.1 -41.0%). The study revealed that DRE possesses potent anti-inflammatory properties in animal models. The results confirm the efficacy of the traditional use of D. reticulata in the treatment of inflammatory diseases.

show abstract

“…[19]. Alpinumisoflavone, carpachromene, lupinifolin, oleanolic acid and erythrodiol are both antioxidant and cytotoxic [26,[44][45][46][47][48][49][50][51][52][53]. The other secondary metabolites have only demonstrated cytotoxic activity.…”

Section: Introductionmentioning

confidence: 99%

In Vitro Antioxidant and Anticancer Properties of Various E. senegalensis Extracts

et al. 2022

View full text Add to dashboard Cite

Although Erythrina senegalensis is a plant widely used in traditional medicine in sub-Saharan Africa, its biological properties have been poorly investigated to date. We first characterized by conventional reactions the composition of several stem bark extracts and evaluated in acellular and cellular assays their pro- or antioxidant properties supported by their high phenolic and flavonoid content, particularly with the methanolic extract. The pro- or antioxidant effects observed did not correlate with their IC50 concentrations against five cancer cell lines determined by MTT assay. Indeed, the CH2Cl2 extract and its ethyl acetate (EtOAc) subfraction appeared more potent although they harbored lower pro- or antioxidant effects. Nevertheless, at equipotent concentration, both extracts induced ER- and mitochondria-derived vacuoles observed by fluorescent microscopy that further led to non-apoptotic cell death. LC coupled to high resolution MS investigations have been performed to identify chemical compounds of the extracts. These investigations highlighted the presence of compounds formerly isolated from E. senegalensis including senegalensein that could be retrieved only in the EtOAc subfraction but also thirteen other compounds, such as 16:3-Glc-stigmasterol and hexadecanoic acid, whose anticancer properties have been previously reported. Nineteen other compounds remain to be identified. In conclusion, E. senegalensis appeared rich in compounds with antioxidant and anticancer properties, supporting its use in traditional practice and its status as a species of interest for further investigations in anticancer drug research.

show abstract

α-Glucosidase inhibitory, antibacterial, and antioxidant activities of natural substances from the wood of Derris reticulata Craib

Cited by 9 publications

References 33 publications

Antimicrobials from Medicinal Plants: An Emergent Strategy to Control Oral Biofilms

Antimicrobials from Medicinal Plants: An Emergent Strategy to Control Oral Biofilms

In vivo Anti-Inflammatory Activity of Derris reticulata Ethanol Extract

In Vitro Antioxidant and Anticancer Properties of Various E. senegalensis Extracts

Contact Info

Product

Resources

About