α-Glucosidase inhibitory activity by the flower buds of Lonicera japonica Thunb

Chemical characterization and anti-hyperglycaemic effects of polyphenol enriched longan (Dimocarpus longan Lour.) pericarp extracts

“…In addition, gallic acid was revealed to be capable of promoting β-cell regeneration (Latha & Daisy, 2011) and (-)-epicatechin was observed to cause a significant rise of glucose consumption in human HepG-2 cells (Lv et al, 2014). The other identified phenolics rutin and 4-O-methylgallic acid displayed potential use in anti-diabetes for inhibition of carbohydrate digestion enzymes, anti-obese and antioxidant activity (Baboota et al, 2013;Pham et al, 2014;Sun et al, 2007;Zhang et al, 2013). Moreover, proanthocyanidins trimer was found to reduce the incidence of type 2 diabetes according to a recent study (Zamora-Ros et al, 2014).…”

Inhibitory kinetics and mechanism of kaempferol on α-glucosidase

“…This enzyme plays a vital role in maintaining the normal physiological function and participates in carbohydrate metabolism that specifically hydrolyzes the a-glucopyranoside bond to release a-glucose from the non-reducing end of the sugar (Lordan, Smyth, Soler-Vila, Stanton, & Ross, 2013). Effective a-glucosidase inhibitors can significantly retard the dietary complex carbohydrate digestion and decrease the postprandial effect of starch consumption on blood glucose levels (Zhang et al, 2013). Acarbose, miglitol and voglibose widely used in clinic were validated to exert anti-postprandial hyperglycemia effect by inhibiting a-glucosidase activities.…”

Investigation of the Safety and Antihyperglycemic Effect of <i>Apios americana</i> Flower Intake as a Food Material in Normal and Diabetic Mice

“…This test was designed to investigate the maltase inhibitory There are a number of reports about the antihyperglycemic effects of natural resources such as Morus alba, Rosa damascena, Lonicera japonica, and Ganoderma lucidum (Yatsunami et al, 2003;Naowaboot et al, 2009;Gholamhoseinian et al, 2009;Zhang et al, 2013;Usui et al, 2007). AFS60 showed 15%…”