α-Ethyltryptamine: A Ratiocinatory Review of a Forgotten Antidepressant
Richard A. Glennon,
Mal̵gorzata Dukat
Abstract:α-Ethyltryptamine (AET) is quite an interesting,
but perhaps
long-forgotten, centrally acting agent. Known for more than 75 years,
AET was once clinically available as an antidepressant but was withdrawn
shortly after its introduction. AET was subsequently controlled as
a U.S. Schedule I substance due to its perceived abuse liability and/or
toxicity but remains an agent of interest. Hallucinogenic tryptamines
(that is, serotonergic psychedelic agents) are now in vogue as novel
and exciting chemotherapeutics fo… Show more
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