Zygosity testing should be encouraged for all same‐sex twins

Craig, Jeffrey M.; Segal, N.L.; Umstad, Mark P.; Cutler, Tessa L.; Keogh, Louise; Hopper, Jennifer; Rankin, Mark; Denton, Jessica Johnson; Derom, Cathérine; Sumathipala, Athula; Harris, J. R. W.

doi:10.1111/1471-0528.13639

Cited by 12 publications

(8 citation statements)

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“…In response to feedback from twins and parents of twins, and from research TRA has conducted (Cutler et al, 2015), TRA has developed an article explaining how parents of twins and professionals can determine zygosity. ‘The importance of zygosity knowledge for twins and science’ was then published in TRA’s online Conversations in Twin Research series (Craig et al, 2019).…”

Section: Knowledge Exchange and Translationmentioning

confidence: 99%

Twins Research Australia: A New Paradigm for Driving Twin Research

et al. 2019

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Twins Research Australia (TRA) is a community of twins and researchers working on health research to benefit everyone, including twins. TRA leads multidisciplinary research through the application of twin and family study designs, with the aim of sustaining long-term twin research that, both now and in the future, gives back to the community. This article summarizes TRA’s recent achievements and future directions, including new methodologies addressing causation, linkage to health, economic and educational administrative datasets and to geospatial data to provide insight into health and disease. We also explain how TRA’s knowledge translation and exchange activities are key to communicating the impact of twin studies to twins and the wider community. Building researcher capability, providing registry resources and partnering with all key stakeholders, particularly the participants, are important for how TRA is advancing twin research to improve health outcomes for society. TRA provides researchers with open access to its vibrant volunteer membership of twins, higher order multiples (multiples) and families who are willing to consider participation in research. Established four decades ago, this resource facilitates and supports research across multiple stages and a breadth of health domains.

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Section: Knowledge Exchange and Translationmentioning

confidence: 99%

Twins Research Australia: A New Paradigm for Driving Twin Research

et al. 2019

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“…Some researchers, physicians and multiple births organization recommend that zygosity testing should be encouraged for all samesex twins [5,6,13,24,25]. Apart from the pros and cons of standard zygosity testing for same-sex twins at birth or earlier age, correct information should be offered by all medical/health professionals to the parents of twins and at the very least, incorrect information should not be offered.…”

Section: The Importance Of Proper Knowledge About Zygosity For Medicamentioning

confidence: 99%

“…Aside from its medical importance [5][6][7], zygosity knowledge can also invoke positive emotional responses in the parents [13,14]. For some twin pairs, to know that they are MZ have special meaning [11].…”

Section: The Importance Of Proper Knowledge About Zygosity For Medicamentioning

confidence: 99%

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Zygosity Misclassification of Recent Young Twins by Maternal Reports in Japan

Ooki¹

2017

J Preg Child Health

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The problem of zygosity misclassification of twins has been paid little attention in Japan. By analyzing maternal reports collected using an internet questionnaire, the author found that around 30% of monozygotic twins were misclassified as dizygotic twins, mainly by obstetricians. On the other hand, the percentage of dizygotic twin pairs misclassified as monozygotic twins was lower. Misclassification was more frequently observed in cases of spontaneous pregnancy compared to iatrogenic pregnancy. The percentage of monozygotic twins misclassified as dizygotic is in very good accordance with that of monozygotic twins having two placentas. The reported number of placentas was very strongly associated with the reported zygosity. Thus, many monozygotic twins in Japan were still misclassified as dizygotic by obstetricians, presumably based solely on the placental findings.

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“…Unfortunately, this attitude sends a misguided message to teenage twins and their families. In a letter published recently in the British Journal of Obstetrics and Gynecology , colleagues and I argued in favor of zygosity testing for all same-sex twins (Craig et al, 2015). The benefits include, but are not limited to, more informed medical decisions, lifestyle choices and sense of self.…”

Section: Identical Twin Models Imentioning

confidence: 99%

Twinsters the Movie: Reared Apart Twins in Real Time/Research Reviews: Heteropagus Twin; Schizophrenia Liability; Twin Study of Epigenetics and Homosexuality; Transgender-Discordant Twins/In the News: The Passing of Jack Yufe; An Unusual Twin Father; Identical Twin Models I; Identical Twin Models II; Twin Marines of World War II

Segal

2016

Twin Res Hum Genet

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The 2015 documentary film Twinsters, tells the story of reared-apart MZ female twins, Samantha (Sam) Futerman and Anaïs Bordier. Born in South Korea, the twins were adopted separately as babies by couples living in the United States (Sam) and France (Anaïs). Their chance discovery of one another and their subsequent reunion and relationship are beautifully captured in the 2015 documentary film, Twinsters. Recent interviews with some of their family members are presented in Twin Research and Human Genetics for the first time. This is followed by brief reviews of recent twin research on a heteropagus twin, schizophrenia liability, epigenetics and homosexuality, and transgender-discordant twins. Finally, some newsworthy items are summarized, including the passing of reared-apart MZ twin Jack Yufe, an unusual twin father; identical twin models I; identical twin models II; and a pair of twin marines.

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Zygosity testing should be encouraged for all same‐sex twins

Cited by 12 publications

References 0 publications

Twins Research Australia: A New Paradigm for Driving Twin Research

Twins Research Australia: A New Paradigm for Driving Twin Research

Zygosity Misclassification of Recent Young Twins by Maternal Reports in Japan

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